The University of Miami Division of Perinatology has the personnel, a predominantly diverse multiethnic low socioeconomic patient population, facilities and research experience needed to participate effectively in the Cooperative Multicenter Maternal-Fetal Medicine Units Network, initiating and participating in the development and implementation of protocols, data analysis, and the publications. Specifically, protocols should have scientific merit, be able to improve maternal/fetal outcome, be cost effective, and have practical value on a large scale basis for all women, especially those with the poorest outcomes (e.g., preterm delivery patients) or with conditions subject to greatest controversy (e.g., gestational diabetes), with a particular commitment to enroll minorities. Jackson is a large obstetric/neonatal facility, delivering more than 7,000 babies in 1994 from women with a vast array of medical/obstetric referrals. While not all prenatal care occurs at Jackson, there are protocols for high risk obstetric referrals between the local clinics and the hospital. The institution is a regionalized tertiary care facility. The academic activities of the perinatal and neonatal programs are recognized nationally. The obstetric team is committed to making a meaningful contribution in the network to address projects which require large scale studies. The Obstetric team has participated in multicenter trials over the last 17 years, more so in the last six years, predominantly in MFU infection and drug studies of antibiotic and triolytic agents. Our center proposes a protocol concept for a study on gestational abnormal glucose metabolism and pregnancy outcome.

Project Start
1996-05-05
Project End
2001-03-31
Budget Start
1997-04-01
Budget End
1998-03-31
Support Year
2
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33146
Clark, Erin A S; Weiner, Steven J; Rouse, Dwight J et al. (2018) Genetic Variation, Magnesium Sulfate Exposure, and Adverse Neurodevelopmental Outcomes Following Preterm Birth. Am J Perinatol 35:1012-1022
Landon, Mark B; Grobman, William A; Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal–Fetal Medicine Units Network (2016) What We Have Learned About Trial of Labor After Cesarean Delivery from the Maternal-Fetal Medicine Units Cesarean Registry. Semin Perinatol 40:281-6
Wapner, Ronald J; Gyamfi-Bannerman, Cynthia; Thom, Elizabeth A et al. (2016) What we have learned about antenatal corticosteroid regimens. Semin Perinatol 40:291-7
Caritis, Steve N; Feghali, Maisa N; Grobman, William A et al. (2016) What we have learned about the role of 17-alpha-hydroxyprogesterone caproate in the prevention of preterm birth. Semin Perinatol 40:273-80
Olson, Gayle; Weiner, Steven J; Rouse, Dwight J et al. (2015) Relation between birth weight and weight and height at the age of 2 in children born preterm. Am J Perinatol 32:591-8
Hirtz, Deborah G; Weiner, Steven J; Bulas, Dorothy et al. (2015) Antenatal Magnesium and Cerebral Palsy in Preterm Infants. J Pediatr 167:834-839.e3
Horton, Amanda L; Lai, Yinglei; Rouse, Dwight J et al. (2015) Effect of magnesium sulfate administration for neuroprotection on latency in women with preterm premature rupture of membranes. Am J Perinatol 32:387-92
Borowski, K S; Clark, E A S; Lai, Y et al. (2015) Neonatal Genetic Variation in Steroid Metabolism and Key Respiratory Function Genes and Perinatal Outcomes in Single and Multiple Courses of Corticosteroids. Am J Perinatol 32:1126-32
Peaceman, Alan M; Lai, Yinglei; Rouse, Dwight J et al. (2015) Length of latency with preterm premature rupture of membranes before 32 weeks' gestation. Am J Perinatol 32:57-62
Varner, Michael W; Marshall, Nicole E; Rouse, Dwight J et al. (2015) The association of cord serum cytokines with neurodevelopmental outcomes. Am J Perinatol 30:115-22

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