Abstract

This application from the University of Pennsylvania School of Medicine and the Children's Hospital of Philadelphia is to participate with the NICHD under a cooperative agreement in an ongoing multicenter Neonatal Research Network (NRN) designed to perform interventional and observational clinical studies in newborn infants, particularly low birth weight infants. The objective of this program is to facilitate the advancement of neonatal care by establishing a network of academic centers that, by rigorous patient evaluation using common protocols, can study the required numbers of patients and can provide answers more rapidly than individual centers acting alone.

Public Health Relevance

The objective of the Neonatal Research Network NRN is to advance the field of Neonatal-Perinatal Medicine by establishing and maintaining a network of academic centers that perform multi-center clinical protocols in a rigorous manner to investigate the safety and efficacy of treatment and management strategies to care for newborn infants, including low birth weight infants.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10HD068244-04
Application #
8643283
Study Section
Special Emphasis Panel (ZHD1-DSR-A (03))
Program Officer
Raju, Tonse N
Project Start
2011-04-01
Project End
2016-03-31
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
4
Fiscal Year
2014
Total Cost
$399,934
Indirect Cost
$17,632

  Institution

Name
University of Pennsylvania
Department
Pediatrics
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Bajaj, Monika; Natarajan, Girija; Shankaran, Seetha et al. (2018) Delivery Room Resuscitation and Short-Term Outcomes in Moderately Preterm Infants. J Pediatr 195:33-38.e2
Chawla, Sanjay; Natarajan, Girija; Chowdhury, Dhuly et al. (2018) Neonatal Morbidities among Moderately Preterm Infants with and without Exposure to Antenatal Corticosteroids. Am J Perinatol 35:1213-1221
Brumbaugh, Jane E; Colaizy, Tarah T; Saha, Shampa et al. (2018) Oral feeding practices and discharge timing for moderately preterm infants. Early Hum Dev 120:46-52
Natarajan, Girija; Shankaran, Seetha; Saha, Shampa et al. (2018) Antecedents and Outcomes of Abnormal Cranial Imaging in Moderately Preterm Infants. J Pediatr 195:66-72.e3
Srinivasan, Lakshmi; Page, Grier; Kirpalani, Haresh et al. (2017) Genome-wide association study of sepsis in extremely premature infants. Arch Dis Child Fetal Neonatal Ed 102:F439-F445
Watterberg, K L; Fernandez, E; Walsh, M C et al. (2017) Barriers to enrollment in a randomized controlled trial of hydrocortisone for cardiovascular insufficiency in term and late preterm newborn infants. J Perinatol 37:1220-1223
Shankaran, Seetha; Laptook, Abbot R; Pappas, Athina et al. (2017) Effect of Depth and Duration of Cooling on Death or Disability at Age 18 Months Among Neonates With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial. JAMA 318:57-67
Jensen, Erik A; Dysart, Kevin C; Gantz, Marie G et al. (2017) Association between Use of Prophylactic Indomethacin and the Risk for Bronchopulmonary Dysplasia in Extremely Preterm Infants. J Pediatr 186:34-40.e2
Puopolo, Karen M; Mukhopadhyay, Sagori; Hansen, Nellie I et al. (2017) Identification of Extremely Premature Infants at Low Risk for Early-Onset Sepsis. Pediatrics 140:
James, Jennifer; Munson, David; DeMauro, Sara B et al. (2017) Outcomes of Preterm Infants following Discussions about Withdrawal or Withholding of Life Support. J Pediatr 190:118-123.e4

Showing the most recent 10 out of 23 publications