Under a cooperative agreement with the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Christiana Care Health Services, Inc. (CCHS) and its partner, Jawaharlal Nehru Medical College (JNMC) of KLE. University, have the long-term objective of continued participation in the Global Network for Women's and Children's Health Research and continued collaboration in the operation of the CCHS-JNMC Research Unit. As a member of a multicenter international research network, the CCHS-JNMC Research Unit will conduct randomized clinical trials and intervention studies focused on reducing major risks to maternal, neonatal, infant, and early childhood health in low and lower-middle income countries. In collaboration with other Global Network participants, CCHS and JNMC will work to strengthen the Global Network research infrastructure, to increase the capacity for women's and children's health research, and to expand scientific knowledge that will lead to improved health practices and outcomes for women, infants, and children.
Specific aims of the CCHS-JNMC Research Unit during the next five-year Global Network funding cycle include: To provide for continued growth and development of the CCHS-JNMC RU which oversees the women's and children's health research program based at JNMC in Belgaum, Karnataka India, and to ensure sustainability of the research infrastructure at JNMC, integrated within the larger KLE University, and extending into surrounding districts served by JNMC and the University; To strengthen the Global Network and its role in international collaborative research by participating in creation of a significant GN research agenda and designing, developing, obtaining support for implementation, and conducting multiple, common research protocols which address the major causes of morbidity and mortality in women and young children in the developing world; To identify and address gaps in maternal and child research and, with other GN participants, to collaboratively implement and evaluate promising health interventions, formative and translational studies, including implementation research; and to disseminate findings.

Public Health Relevance

Continued participation in Global Network activities will strengthen the research capabilities of the CCHSJNMC Research Unit, facilitate additional meritorious research, and lead to formulation of policy and programs in India and elsewhere that will improve maternal, neonatal, infant and childhood health status. The CCHS-JNMC Research Unit has been a highly productive partner in the research agenda of the Global Network for over 10 years and the unit can be a source of future Global Network strength and credibility.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10HD076457-03
Application #
8842154
Study Section
Special Emphasis Panel (ZHD1)
Program Officer
Raju, Tonse N
Project Start
2013-07-01
Project End
2016-03-31
Budget Start
2015-05-01
Budget End
2016-03-31
Support Year
3
Fiscal Year
2015
Total Cost
Indirect Cost
Name
Christiana Care Health Services, Inc.
Department
Type
DUNS #
077069243
City
Newark
State
DE
Country
United States
Zip Code
19713
Pasha, O; McClure, E M; Saleem, S et al. (2018) A prospective cause of death classification system for maternal deaths in low and middle-income countries: results from the Global Network Maternal Newborn Health Registry. BJOG 125:1137-1143
McClure, E M; Garces, A; Saleem, S et al. (2018) Global Network for Women's and Children's Health Research: probable causes of stillbirth in low- and middle-income countries using a prospectively defined classification system. BJOG 125:131-138
Short, Vanessa L; Geller, Stacie E; Moore, Janet L et al. (2018) The Relationship between Body Mass Index in Pregnancy and Adverse Maternal, Perinatal, and Neonatal Outcomes in Rural India and Pakistan. Am J Perinatol 35:844-851
Hoffman, Matthew K; Goudar, Shivaprasad S; Kodkany, Bhalachandra S et al. (2017) A description of the methods of the aspirin supplementation for pregnancy indicated risk reduction in nulliparas (ASPIRIN) study. BMC Pregnancy Childbirth 17:135
Goldenberg, Robert L; Saleem, Sarah; Ali, Sumera et al. (2017) Maternal near miss in low-resource areas. Int J Gynaecol Obstet 138:347-355
Hambidge, K Michael; Krebs, Nancy F; Garcés, Ana et al. (2017) Anthropometric indices for non-pregnant women of childbearing age differ widely among four low-middle income populations. BMC Public Health 18:45
Harrison, Margo S; Pasha, Omrana; Saleem, Sarah et al. (2017) A prospective study of maternal, fetal and neonatal outcomes in the setting of cesarean section in low- and middle-income countries. Acta Obstet Gynecol Scand 96:410-420
Garces, Ana L; McClure, Elizabeth M; Pérez, Wilton et al. (2017) The Global Network Neonatal Cause of Death algorithm for low-resource settings. Acta Paediatr 106:904-911
Chomba, Elwyn; Carlo, Wally A; Goudar, Shivaprasad S et al. (2017) Effects of Essential Newborn Care Training on Fresh Stillbirths and Early Neonatal Deaths by Maternal Education. Neonatology 111:61-67
Klein, Karen; McClure, Elizabeth M; Colaci, Daniela et al. (2016) The Antenatal Corticosteroids Trial (ACT): a secondary analysis to explore site differences in a multi-country trial. Reprod Health 13:64

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