We propose to organize a series of three yearly meetings devoted to definition and measurement of hyperkinetic movement disorders in childhood. The taskforce on childhood motor disorders has previously established consensus definitions and measurement technology recommendations for hypertonic disorders and negative signs. Hyperkinetic disorders represent the third major category of pediatric motor disorders. In the first of the three meetings, consensus definitions relevant to children will be established for the terms """"""""chorea"""""""", """"""""choreoathetosis"""""""", """"""""hyperkinetic dystonia"""""""", and """"""""tremor"""""""". In the second meeting, current scales and technology for diagnosis and quantification of these impairments will be discussed. In the third meeting, new scales and technology for diagnosis and quantification will be demonstrated. The result of this series of meetings will be a consensus statement on definitions, identification of gaps in current assessment tools, and specific recommendations for the development of new measurement tools. Definitions and measurement tools are essential for communication between clinicians, inclusion of children in clinical trials, and measurement of outcomes of treatment in the clinic and in clinical trials. This project will provide consensus definitions and work toward the development of measurement tools for children with hyperkinetic disorders. The result will be definitions and recommendations that will improve the effectiveness and success of clinical trials for children with disorders of movement. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Conference--Cooperative Agreements (U13)
Project #
5U13NS061384-02
Application #
7629739
Study Section
Special Emphasis Panel (ZNS1-SRB-W (28))
Program Officer
Chen, Daofen
Project Start
2007-09-30
Project End
2010-08-31
Budget Start
2008-09-01
Budget End
2009-08-31
Support Year
2
Fiscal Year
2008
Total Cost
$65,000
Indirect Cost
Name
Stanford University
Department
Neurology
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
Sukal-Moulton, Theresa; Gaebler-Spira, Deborah; Krosschell, Kristin J (2018) The validity and reliability of the Test of Arm Selective Control for children with cerebral palsy: a prospective cross-sectional study. Dev Med Child Neurol 60:374-381
Bertucco, Matteo; Sanger, Terence D (2015) Current and emerging strategies for treatment of childhood dystonia. J Hand Ther 28:185-93; quiz 194
Musselman, Kristin E; Stoyanov, Cristina T; Marasigan, Rhul et al. (2014) Prevalence of ataxia in children: a systematic review. Neurology 82:80-9
Sanger, Terence D; Chen, Daofen; Fehlings, Darcy L et al. (2010) Definition and classification of hyperkinetic movements in childhood. Mov Disord 25:1538-49