Salmonella accounts for an estimated 1.4 million illnesses, resulting in 16,000hospitalizations, and 582 deaths in the United States each year. The incidence ofsalmonellosis within the U.S. differs from state to state and in state. These differencescannot be explained entirely by differences in population density, cultural/ethniccustoms, or food-distribution networks. These regional differences in disease incidenceare also reflected in Salmonella serovar distribution. We do not know or understand whatmight explain this geographic scattering of Salmonella infection in the U.S. Part of theanswer lies in identifying alternate reservoirs, such as pets. A better understanding ofthe transmission dynamics of Salmonella in pets will helps us understand the role ofthese unique companions, in the distribution dynamics of Salmonella and humanillnesses. This proposal explores the role that the food sources of our pets, their lifestyle,human culture, and geographic region may have on the distribution of Salmonellaserovars and strains in companion animals and ultimately in cases of human sporadicsalmonellosis. We propose to do this by culturing fecal samples from symptomatic andasymptomatic dogs across GA. We will determine prevalence of Salmonella both inhealthy and sick pets. Salmonella serovars and strains will be then typed and analyzedto determine if any correlations exists which the geographical location of the pets home,their lifestyle or any other characteristic present in our questionnaire.

Public Health Relevance

Salmonella is a zoonotic agent that causes over a million illnesses in the U.S. alone. Although food sources are the main form of infection to humans, there is growing evidence that pets and their food are sources of Salmonella. Nevertheless, very little is known on the true prevalence of Salmonella in pets in the U.S. today. Understanding the epidemiology of Salmonella at the human-pet interface is crucial in understanding and ultimately reducing disease in people caused by Salmonella.

Agency
National Institute of Health (NIH)
Institute
Food and Drug Administration (FDA)
Type
Research Demonstration--Cooperative Agreements (U18)
Project #
1U18FD004318-01
Application #
8320585
Study Section
Special Emphasis Panel (ZFD1-SRC (99))
Project Start
2011-09-16
Project End
2013-09-15
Budget Start
2011-09-16
Budget End
2012-09-15
Support Year
1
Fiscal Year
2011
Total Cost
Indirect Cost
Name
University of Georgia
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
004315578
City
Athens
State
GA
Country
United States
Zip Code
30602