Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Liu, Z; Wong, J T (1999) Proliferative and regenerative capacities of CD4(+) T cells upon TCR stimulation. Clin Immunol 93:16-23
Shankar, P; Xu, Z; Lieberman, J (1999) Viral-specific cytotoxic T lymphocytes lyse human immunodeficiency virus-infected primary T lymphocytes by the granule exocytosis pathway. Blood 94:3084-93
Trimble, L A; Xu, Z; Lieberman, J (1999) Clonal expansion of antigen-specific CD8+ cytotoxic T lymphocytes is regulated by late exposure to serum to prevent apoptosis. J Immunol Methods 225:39-52
Trimble, L A; Lieberman, J (1998) Circulating CD8 T lymphocytes in human immunodeficiency virus-infected individuals have impaired function and downmodulate CD3 zeta, the signaling chain of the T-cell receptor complex. Blood 91:585-94
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Buchsbaum, R J; Fabry, J A; Lieberman, J (1996) EBV-specific cytotoxic T lymphocytes protect against human EBV-associated lymphoma in scid mice. Immunol Lett 52:145-52
Srinivas, R V; Su, T; Trimble, L A et al. (1995) Enhanced susceptibility to human immunodeficiency virus infection in CD4+ T lymphocytes genetically deficient in CD43. AIDS Res Hum Retroviruses 11:1015-21
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