As a non-profit research institution, Sage Bionetworks is driven by the impact that our science can create, either directly, or with collaborators. We have created open bioinformatics and data resources as part of every large-scale research project in which we have participated, covering a diverse set of projects involving clinical, imaging, `omics, and mobile sensor data related to research in oncology. Over the past 4 years, we have developed Synapse, an informatics platform for hosting scientific data, code, and knowledge, and have established an outstanding track record of effective interactions that engage large scale research consortia. We have tested the Synapse platform by supporting research efforts that required dozens to hundreds of scientists to share data, analysis code, and results in real time. This platform, and the activities of Sage's data scientists and curators, form the basis for the Resource Coordinating Hub. These efforts provide a model for our interactions with the other CSBC and PS-ON centers in the Collaboration and Pilot Project Hub. One of our most successful strategies for forming and engaging research communities has been to organize and run crowdsourced competitions called DREAM Challenges will form the core of the Outreach Hub.

Public Health Relevance

Sage Bionetworks has created open bioinformatics and data resources as part of every large-scale research project in which we have participated, covering a diverse set of projects involving clinical, imaging, `omics, and mobile sensor data related to research in oncology. Though supporting these projects, we have developed the Synapse informatics platform for hosting scientific data, code, and knowledge; we have established an outstanding track record of effective interactions that engage large scale research consortia; we have led the development of over a dozen community challenges as part of the DREAM program to engage a diverse scientific audience. We will apply these experiences as an engaged Coordinating Center for the CSBC and PS-ON programs.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Resource-Related Research Projects--Cooperative Agreements (U24)
Project #
5U24CA209923-03
Application #
9527049
Study Section
Special Emphasis Panel (ZCA1)
Program Officer
Hughes, Shannon K
Project Start
2016-08-01
Project End
2021-07-31
Budget Start
2018-08-01
Budget End
2019-07-31
Support Year
3
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Sage Bionetworks
Department
Type
DUNS #
830977117
City
Seattle
State
WA
Country
United States
Zip Code
98121