HD iPSC Consortium (2017) Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice. Nat Neurosci 20:648-660
|
Lim, Ryan G; Quan, Chris; Reyes-Ortiz, Andrea M et al. (2017) Huntington's Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits. Cell Rep 19:1365-1377
|
Haston, Kelly M; Finkbeiner, Steven (2016) Clinical Trials in a Dish: The Potential of Pluripotent Stem Cells to Develop Therapies for Neurodegenerative Diseases. Annu Rev Pharmacol Toxicol 56:489-510
|
Finkbeiner, Steven; Frumkin, Michael; Kassner, Paul D (2015) Cell-based screening: extracting meaning from complex data. Neuron 86:160-74
|
Hatada, Seigo; Subramanian, Aparna; Mandefro, Berhan et al. (2015) Low-Dose Irradiation Enhances Gene Targeting in Human Pluripotent Stem Cells. Stem Cells Transl Med 4:998-1010
|
Mattis, Virginia B; Tom, Colton; Akimov, Sergey et al. (2015) HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity. Hum Mol Genet 24:3257-71
|
Skibinski, Gaia; Nakamura, Ken; Cookson, Mark R et al. (2014) Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies. J Neurosci 34:418-33
|
Ross, Christopher A; Akimov, Sergey S (2014) Human-induced pluripotent stem cells: potential for neurodegenerative diseases. Hum Mol Genet 23:R17-26
|
Shelley, Brandon C; Gowing, Geneviève; Svendsen, Clive N (2014) A cGMP-applicable expansion method for aggregates of human neural stem and progenitor cells derived from pluripotent stem cells or fetal brain tissue. J Vis Exp :
|
Barmada, Sami J; Serio, Andrea; Arjun, Arpana et al. (2014) Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models. Nat Chem Biol 10:677-85
|
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