The nonhuman primate and laboratory core will be a joint venture between the Yerkes NationalPrimate Research Center, Emory University, Atlanta, Georgia and the Tulane National PrimateResearch Center, Tulane University, Covington, Louisiana. The central objective of the nonhumanprimate animal and laboratory core is to provide highly integrated administrative support,specialized expertise, clinical management and laboratory assays to project leaders and individualinvestigators in the conduct of protocols using nonhuman primates. The animal and laboratory corewill acquire, house and provide care for the nonhuman primates used in the RCE. The core alsowill be responsible both for comprehensive clinical care of animals and the conduct of experimentalprocedures such as immunizing, collecting blood and other biological samples, biopsies, and suchother procedures as required by investigators. Both the Tulane and the Yerkes National PrimateResearch Centers have broad experience and expertise in the conduct of research usingnonhuman primates as well as an array of animal housing facilities (including breeding colonies)and laboratory support services. Both Centers also have an extensive history in working withinvestigators from outside institutions as part of the NIH/NCRR funded primate national resourcesprogram and each is fully accredited by AAALAC. Both Primate Centers have been operational forover forty years as NCRR supported national resources. Specifically, in the first year of the project,support will be provided to the following identified research or developmental projects, and suchothers as may develop:a. New Vaccine Concepts for Poxvirus and Poxvirus Virulence Genes (Program 1)b. Development of Immune Modulation Strategies to Optimize Innate Immune Response to SelectAgent Infections (Proram 6)c. Strategies to Optimize Mucosal Immune Response to Anthrax Protective Antigen (Program 7)
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