The MARGE Career Development and Training Program is divided into two parts. The overridingobjective of the first part, the Individual Career Development Support Program, is to bring a cadre ofbright, motivated, young scientists into the broad area of biodefense and emerging infectious diseasesresearch. Two Career Development Awards be offered in the amount of $150,000 per year for two years ofsupervised study and research for professionals who have the potential to develop into productive scientificinvestigators. This Program will enhance and support the MARCE Strategic Plan in several ways. First, theaddition of new investigators will complement the existing interactions between established MARCEinvestigators and inject fresh ideas into the field. Second, the addition of the recipients' projects will furtherexpand the research portfolio. Third, Career Development projects will enhance synergies with the existingResearch Programs through ties to the sub-themes of those Programs. For the second part of this Program,the MARCE will offer the following Group Career Development Activities based on a needs assessmentand the success of these training courses in the first funding period: 1) BSL-3 Laboratory BiosafetyTraining. This three-day course offered at the U. of Maryland will feature lectures, group learning activities,demonstrations, and hands-on training for BSL-3 experiments and aerobiology; 2) Media Training for BioScientists in Preparation for Public Health Emergencies. This one day-course offered by the GeorgeWashington U. will prepare scientists to become effective subject matter communicators during public healthemergencies; 3) Training in Good Manufacturing Practices, Good Laboratory Practices and ProcessDevelopment. This two-day course at the Sanofi Pasteur Vaccines manufacturing facilities will cover GMP,GLP, process development, regulatory issues and manufacture; and 4) Training in the Complexity ofResponse to Biological Emergencies. The U. of Maryland Center for Health and Homeland Security willhost an interactive two-day workshop where national and international experts discuss how they will preparefor and respond to a bioterrorist attack or emerging infectious disease outbreak. In addition, a ClinicalIssues Training Committee, staffed by infectious disease experts at the major MARCE institutions, will beprepared to rapidly offer instruction on emerging infections or biodefense issues in the face of an event.Together, the Career and Training Programs will increase the overall pool of trained investigators andqualified researchers in this field.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
3U54AI057168-05S2
Application #
7680528
Study Section
Special Emphasis Panel (ZAI1-NBS-M (M2))
Project Start
2008-03-01
Project End
2009-02-28
Budget Start
2008-03-01
Budget End
2009-02-28
Support Year
5
Fiscal Year
2008
Total Cost
$54,036
Indirect Cost
Name
University of Maryland Baltimore
Department
Type
DUNS #
188435911
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Champion, Anna E; Bandara, Aloka B; Mohapatra, Nrusingh et al. (2018) Further Characterization of the Capsule-Like Complex (CLC) Produced by Francisella tularensis Subspecies tularensis: Protective Efficacy and Similarity to Outer Membrane Vesicles. Front Cell Infect Microbiol 8:182
Bridge, Dacie R; Blum, Faith C; Jang, Sungil et al. (2017) Creation and Initial Characterization of Isogenic Helicobacter pylori CagA EPIYA Variants Reveals Differential Activation of Host Cell Signaling Pathways. Sci Rep 7:11057
Kaempfer, Raymond; Popugailo, Andrey; Levy, Revital et al. (2017) Bacterial superantigen toxins induce a lethal cytokine storm by enhancing B7-2/CD28 costimulatory receptor engagement, a critical immune checkpoint. Receptors Clin Investig 4:
Molleston, Jerome M; Cherry, Sara (2017) Attacked from All Sides: RNA Decay in Antiviral Defense. Viruses 9:
Cifuentes-Muñoz, Nicolás; Sun, Weina; Ray, Greeshma et al. (2017) Mutations in the Transmembrane Domain and Cytoplasmic Tail of Hendra Virus Fusion Protein Disrupt Virus-Like-Particle Assembly. J Virol 91:
Sarute, Nicolás; Ross, Susan R (2017) New World Arenavirus Biology. Annu Rev Virol 4:141-158
Ramachandran, Girish; Aheto, Komi; Shirtliff, Mark E et al. (2016) Poor biofilm-forming ability and long-term survival of invasive Salmonella Typhimurium ST313. Pathog Dis 74:
Wahid, Rezwanul; Fresnay, Stephanie; Levine, Myron M et al. (2016) Cross-reactive multifunctional CD4+ T cell responses against Salmonella enterica serovars Typhi, Paratyphi A and Paratyphi B in humans following immunization with live oral typhoid vaccine Ty21a. Clin Immunol 173:87-95
Li, Huiguang; Hwang, Young; Perry, Kay et al. (2016) Structure and Metal Binding Properties of a Poxvirus Resolvase. J Biol Chem 291:11094-104
Chou, Yi-Ying; Cuevas, Christian; Carocci, Margot et al. (2016) Identification and Characterization of a Novel Broad-Spectrum Virus Entry Inhibitor. J Virol 90:4494-4510

Showing the most recent 10 out of 375 publications