The Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) Training (Career Development) Component will use CEGIR resources and opportunities available at each site to create a program that will train new investigators in clinical and translational research, designed to ultimately enhance the likelihood of academic success for the investigators in training. This consortium represents an unparalleled opportunity for new clinical investigators to obtain training in the rare diseases eosinophilic esophagitis (EoE), eosinophilic gastritis (EG), and eosinophilic colitis (EC) and to enhance their career development. Each CEGIR site has experience and resources to aid career development of new investigators in clinical investigation and translational research and has new investigators that would be outstanding CEGIR Trainee candidates. The specific goals ofthe CEGIR Training (Career Development) Component are 1) to enable CEGIR Trainees to become independent clinical and/or translational investigators; 2) to aid CEGIR Trainees in developing a broad understanding ofthe basic, translational, and clinical science pertinent to the immunobiology, pathogenesis, and genetics of EoE, EG, and EC via didactic instruction; and 3) to facilitate CEGIR Trainee networking and integration in the EoE, EG, and EC research community. These goals will be achieved through a variety of important interventions including recruiting stellar candidates, encouraging inclusion of underrepresented minorities, didactic lectures, the Biannual CEGIR Education Symposium, interactions with established researchers and patient advocacy groups (PAGs) in EoE, EG, and EC, opportunities to visit centers of excellence to learn new techniques, and active involvement in other research activities of CEGIR.

Public Health Relevance

Increasing the number and quality of clinician researchers studying eosinophilic esophagitis, eosinophilic gastritis, and eosinophilic colitis will improve current and future patient care. We will train clinician researchers about these rare diseases while enhancing the understanding and treatment of them throughout the community. Ultimately, this training is designed to improve patient outcomes while advancing the development of a cure.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54AI117804-05
Application #
9539706
Study Section
Special Emphasis Panel (ZTR1)
Project Start
Project End
Budget Start
2018-08-01
Budget End
2019-07-31
Support Year
5
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Dellon, Evan S; Liacouras, Chris A; Molina-Infante, Javier et al. (2018) Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference. Gastroenterology 155:1022-1033.e10
Dellon, Evan S; Hirano, Ikuo (2018) Epidemiology and Natural History of Eosinophilic Esophagitis. Gastroenterology 154:319-332.e3
Wright, Benjamin L; Nguyen, Nathalie; Shim, Kelly P et al. (2018) Increased GATA-3 and T-bet expression in eosinophilic esophagitis versus gastroesophageal reflux disease. J Allergy Clin Immunol 141:1919-1921.e5
Godwin, Bridget; Liacouras, Chris; Mehta, Vijay et al. (2018) A Review of Tertiary Referrals for Management of Pediatric Esophageal Eosinophilia. Front Pediatr 6:173
Hiremath, Girish; Kodroff, Ellyn; Strobel, Mary J et al. (2018) Individuals affected by eosinophilic gastrointestinal disorders have complex unmet needs and frequently experience unique barriers to care. Clin Res Hepatol Gastroenterol 42:483-493
Hiremath, Girish; Vaezi, Michael F; Gupta, Sandeep K et al. (2018) Management of Esophageal Food Impaction Varies Among Gastroenterologists and Affects Identification of Eosinophilic Esophagitis. Dig Dis Sci 63:1428-1437
Patel, Ronak Vashi; Hirano, Ikuo (2018) New Developments in the Diagnosis, Therapy, and Monitoring of Eosinophilic Esophagitis. Curr Treat Options Gastroenterol 16:15-26
Jensen, Elizabeth T; Dellon, Evan S (2018) Environmental factors and eosinophilic esophagitis. J Allergy Clin Immunol 142:32-40
Egan, Maureen; Atkins, Dan (2018) What Is the Relationship Between Eosinophilic Esophagitis (EoE) and Aeroallergens? Implications for Allergen Immunotherapy. Curr Allergy Asthma Rep 18:43
Khoury, Paneez; Akuthota, Praveen; Ackerman, Steven J et al. (2018) Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD). J Leukoc Biol 104:69-83

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