MW CTR-IN Program -- Abstract The diverse Mountain West (MW) population continues to be plagued by high rates of health disparities (HD) and lower life expectancy rates when compared to the rest of the US1. The MW Clinical and Translational Research Infrastructure Network (CTR-IN) was established in 2013. During the last 4 years, we have created an impactful and transformative research network with our 13 MW university partners located geographically among 7 Institutional Development Award (IDeA) states to address the health disparities affecting the MW population in Year 6-10. Yet, despite this huge territory and an overall insufficient regional clinical research infrastructure, we have successfully created and implemented a highly functional CTR-IN program in the last 4 years that has seeded a transformative culture of CTR among the 13 MW universities. Over the last 4 years, we created and implemented 4 highly productive Cores consisting of Pilot Grants, Biostatistics, Professional Development and Administration that have positioned us to focus on addressing the health disparities in our MW region for the next 5 years. Hence, we propose to expand the original mission of the MW CTR-IN Program by further enhancing the research infrastructure in the 7 MW IDeA states for the conduct of rigorous clinical and translational research (CTR) focused on health disparities. The 3 major themes of our proposal are as follows: (1) CTR focused on the MW health disparities; (2) Priority on the professional development of the MW junior faculty investigators; and (3) Providing leadership to the other IDeA programs & Universities in the MW region. Hence, we are proposing 4 major aims to focus our activities on the health disparities in the MW region through rigorous CTR as follows:
Aim 1. Enhance the infrastructure and human resources required to conduct rigorous CTR in our 7 IDeA MW states at our 13 major public university partners.
Aim 2. Focus on the health disparities experienced by our diverse populations such as the medically underserved and/or rural communities in our 7 IDeA MW states through our CTR programs.
Aim 3. Enhance the ability of our IDeA universities and investigators to develop competitive clinical and translational research grants for subsequent extramural funding.
Aim 4. Foster increased collaboration and coordination of clinical and translational activities within and across our 7 MW IDeA states and our 13 MW university partners.

Public Health Relevance

In our 7 Mountain West (MW) IDeA states, health disparities are a major health crisis. During the past four years, the MW CTR-IN program has established a research infrastructure working in conjunction with our 13 MW University partners located geographically among our 7 IDeA states. The MW CTR-IN program plans to expand the original mission of the CTR-IN program by further enhancing the research infrastructure of the MW region for the conduct of rigorous clinical and translational research to focus on health disparities in years 6-10.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
2U54GM104944-06
Application #
9574864
Study Section
Special Emphasis Panel (ZGM1)
Program Officer
Gorospe, Rafael
Project Start
2013-09-15
Project End
2023-06-30
Budget Start
2018-08-08
Budget End
2019-06-30
Support Year
6
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Nevada Las Vegas
Department
Type
Sch Allied Health Professions
DUNS #
098377336
City
Las Vegas
State
NV
Country
United States
Zip Code
89154
Copley Salem, Christian; Ulrich, Craig; Quilici, David et al. (2018) Mechanical strain induced phospho-proteomic signaling in uterine smooth muscle cells. J Biomech 73:99-107
Bakhireva, Ludmila N; Lowe, Jean; Garrison, Laura M et al. (2018) Role of caregiver-reported outcomes in identification of children with prenatal alcohol exposure during the first year of life. Pediatr Res 84:362-370
Gandhi, Krupa; Lim, Eunjung; Davis, James et al. (2018) Racial Disparities in Health Service Utilization Among Medicare Fee-for-Service Beneficiaries Adjusting for Multiple Chronic Conditions. J Aging Health 30:1224-1243
Rowland, Andrew S; Skipper, Betty J; Rabiner, David L et al. (2018) Attention-Deficit/Hyperactivity Disorder (ADHD): Interaction between socioeconomic status and parental history of ADHD determines prevalence. J Child Psychol Psychiatry 59:213-222
Eggleston, Jeffrey D; Harry, John R; Dufek, Janet S (2018) Lower extremity joint stiffness during walking distinguishes children with and without autism. Hum Mov Sci 62:25-33
Banna, Jinan; Bersamin, Andrea (2018) Community involvement in design, implementation and evaluation of nutrition interventions to reduce chronic diseases in indigenous populations in the U.S.: a systematic review. Int J Equity Health 17:116
Xiao, X; Roohani, D; Wu, Q (2018) Genetic profiling of decreased bone mineral density in an independent sample of Caucasian women. Osteoporos Int 29:1807-1814
Lawrence, Braden J; Luciano, Mark; Tew, John et al. (2018) Cardiac-Related Spinal Cord Tissue Motion at the Foramen Magnum is Increased in Patients with Type I Chiari Malformation and Decreases Postdecompression Surgery. World Neurosurg 116:e298-e307
Fakhry, Carole; Qeadan, Fares; Gilman, Robert H et al. (2018) Oral sampling methods are associated with differences in immune marker concentrations. Laryngoscope 128:E214-E221
Lim, Eunjung; Gandhi, Krupa; Siriwardhana, Chathura et al. (2018) Racial and ethnic differences in mental health service utilization among the Hawaii medicaid population. J Ment Health :1-10

Showing the most recent 10 out of 109 publications