Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
3U54HG003916-03S1
Application #
7499912
Study Section
Special Emphasis Panel (ZMH1-ERB-Y (02))
Program Officer
Ozenberger, Bradley
Project Start
2005-07-01
Project End
2009-06-30
Budget Start
2007-07-01
Budget End
2009-06-30
Support Year
3
Fiscal Year
2007
Total Cost
$238,750
Indirect Cost
Name
Sanford-Burnham Medical Research Institute
Department
Type
DUNS #
020520466
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Ma, Chen-Ting; Sergienko, Eduard A (2016) Time-Resolved Fluorescence Assays. Methods Mol Biol 1439:131-42
Rozanov, Dmitri; Cheltsov, Anton; Sergienko, Eduard et al. (2015) TRAIL-Based High Throughput Screening Reveals a Link between TRAIL-Mediated Apoptosis and Glutathione Reductase, a Key Component of Oxidative Stress Response. PLoS One 10:e0129566
Tautz, Lutz; Sergienko, Eduard A (2013) High-throughput screening for protein tyrosine phosphatase activity modulators. Methods Mol Biol 1053:223-40
Prigozhina, Natalie L; Heisel, Andrew J; Seldeen, Jordan R et al. (2013) Amphiphilic suramin dissolves Matrigel, causing an 'inhibition' artefact within in vitro angiogenesis assays. Int J Exp Pathol 94:412-7
Chung, Thomas D Y (2013) Robotic implementation of assays: tissue-nonspecific alkaline phosphatase (TNAP) case study. Methods Mol Biol 1053:53-84
Dahl, Russell; Bravo, Yalda; Sharma, Vandana et al. (2011) Potent, selective, and orally available benzoisothiazolone phosphomannose isomerase inhibitors as probes for congenital disorder of glycosylation Ia. J Med Chem 54:3661-8
Correa, Ricardo G; Khan, Pasha M; Askari, Nadav et al. (2011) Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors. Chem Biol 18:825-32
Chung, Thomas D Y; Sergienko, Eduard; Millan, Jose Luis (2010) Assay format as a critical success factor for identification of novel inhibitor chemotypes of tissue-nonspecific alkaline phosphatase from high-throughput screening. Molecules 15:3010-37
Lanier, Marion; Sergienko, Eduard; Simao, Ana Maria et al. (2010) Design and synthesis of selective inhibitors of placental alkaline phosphatase. Bioorg Med Chem 18:573-9
Sergienko, Eduard A; Millán, José Luis (2010) High-throughput screening of tissue-nonspecific alkaline phosphatase for identification of effectors with diverse modes of action. Nat Protoc 5:1431-9

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