Scholar Program (Plan 1) The Southwestern Comprehensive Sickle Cell Center (SCSCC) will again include as a key component of its grant application a plan (Plan 1) for a Sickle Cell Scholar Program. Its purpose will be to offer comprehensive multidisciplinary training to post-doctoral professionals who desire to excel at a career in investigation, teaching, and patient care involving sickle cell disease. The milieu at UT Southwestern and its affiliated institutions for providing such training is outstanding. For over 15 years the Pediatric Hematology- Oncology Program has been the recipient of a T32 NRSA Institutional Training Grant, and UT Southwestern is also recipient of K30 and K12 institutional clinical research support grants from NIH. Moreover, the University administration has provided major resources to establish a new Department of Clinical Sciences, which offers advanced degrees in patient-oriented research and an expansive curriculum of course work, seminars, and structured mentoring. The Center's basic science research infrastructure, one of the strongest in the country, will support scholars who choose a bench research pathway. During the current (2003 - 2008) grant cycle two Sickle Cell Scholars have been appointed and have excelled in their respective research domains of neurological and renal complications of sickle cell disease. Individuals from all disciplines, whether they are at UT Southwestern or another participating institution in Texas, Oklahoma, and Florida, are eligible as scholars, and an active recruitment effort is planned with particular emphasis on attracting minority scientists to the program. Scholars Selection and Scholar Advisory Committees will continue to identify and nominate candidates and then guide them and monitor their progress. The SCSCC remains well positioned to train tomorrow's leaders in sickle cell research.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54HL070588-07
Application #
7880648
Study Section
Special Emphasis Panel (ZHL1)
Project Start
Project End
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
7
Fiscal Year
2009
Total Cost
$175,505
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Type
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
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Vetter, Courtney L; Buchanan, George R; Quinn, Charles T (2014) Burden of diagnostic radiation exposure in children with sickle cell disease. Pediatr Blood Cancer 61:1322-4
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Dale, Juanita Conkin; Cochran, Cindy J; Roy, Lonnie et al. (2011) Health-related quality of life in children and adolescents with sickle cell disease. J Pediatr Health Care 25:208-15
McCavit, Timothy L; Quinn, Charles T; Techasaensiri, Chonnamet et al. (2011) Increase in invasive Streptococcus pneumoniae infections in children with sickle cell disease since pneumococcal conjugate vaccine licensure. J Pediatr 158:505-7
Quinn, Charles T; Stuart, Marie J; Kesler, Karen et al. (2011) Tapered oral dexamethasone for the acute chest syndrome of sickle cell disease. Br J Haematol 155:263-7
Becker, Amy M (2011) Sickle cell nephropathy: challenging the conventional wisdom. Pediatr Nephrol 26:2099-109
Neelam, Sudha; Kakhniashvili, David G; Wilkens, Stephan et al. (2011) Functional 20S proteasomes in mature human red blood cells. Exp Biol Med (Maywood) 236:580-91
Ghatpande, Swati S; Choudhary, Pankaj K; Quinn, Charles T et al. (2010) In vivo pharmaco-proteomic analysis of hydroxyurea induced changes in the sickle red blood cell membrane proteome. J Proteomics 73:619-26

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