The University of the District of Columbia (UDC) and the Lombardi Cancer Center (LCC) are proposing to establish a planning U56 funded Partnership that will build upon their successes in a currently funded P20 Partnership. The U56-funded Partnership will focus exclusively on Cancer Prevention and Control. This is a highly relevant focus for the District of Columbia (DC), which has among the higher cancer death rates in the nation.
The specific aims are: (1) to establish a Planning and Evaluation Core that will identify priorities, evaluate progress and determine success; (2) to establish a Developmental Core that will begin with 4 pilot projects and new faculty recruits and; (3) to establish a LCC and UDC jointly taught UDC masters program in Cancer Biology, Prevention and Control. The goal of this partnership is to allow the investigators to develop mutually beneficial collaborations worthy of new peer-reviewed funding. Thus, this U56 mechanism is focused on obtaining pilot data that will allow us to test future hypotheses, rather than answer current research questions that would lead to publications. In the first two years, the pilot projects are focused on the structure of data needed to obtain grants such as R01's, while it is anticipated that in the later years we will focus on data to obtain a U54 Partnership grant. The four pilot projects span the range of cancer control. These include: 1) a nutrition project involving low-income pregnant women; 2) use of counter-marketing techniques for prevention of cigarette smoking by packaging data from tobacco industry documents targeting African Americans; 3) enhancing enrollment for minorities in clinical trials, and; 4) identifying methods to integrate palliative care for minorities in medical school curricula. We also will establish a jointly conducted masters program in Cancer Biology, Prevention and Control, emphasizing the need for basis sciences and cancer control for more effective cancer control research, and stimulating minority students to pursue research careers. This U56 Partnership is feasible and the outcomes are achievable because with the P20 funding we have found that our faculty can work together on both research and teaching projects. We have identified that the strengths and limitations of each institution are most complementary in the area of cancer prevention and control. Each institution has expressed in writing a commitment to insure the success of the Partnership.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Exploratory Grants--Cooperative Agreements (U56)
Project #
3U56CA101429-05S1
Application #
7691911
Study Section
Special Emphasis Panel (ZCA1-SRRB-7 (J1))
Program Officer
Aguila, H Nelson
Project Start
2003-09-15
Project End
2009-08-31
Budget Start
2007-09-06
Budget End
2009-08-31
Support Year
5
Fiscal Year
2008
Total Cost
$168,443
Indirect Cost
Name
Georgetown University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Luta, George; Ford, Melissa B; Bondy, Melissa et al. (2013) Bayesian sensitivity analysis methods to evaluate bias due to misclassification and missing data using informative priors and external validation data. Cancer Epidemiol 37:121-6
Sheppard, Vanessa B; Huei-yu Wang, Judy; Eng-Wong, Jennifer et al. (2013) Promoting mammography adherence in underserved women: the telephone coaching adherence study. Contemp Clin Trials 35:35-42
Karve, Tejaswita M; Preet, Anju; Sneed, Rosie et al. (2012) BRCA1 regulates follistatin function in ovarian cancer and human ovarian surface epithelial cells. PLoS One 7:e37697
Graves, Kristi D; Gatammah, Rhoda; Peshkin, Beth N et al. (2011) BRCA1/2 genetic testing uptake and psychosocial outcomes in men. Fam Cancer 10:213-23
Khwaja, Fatima S; Wynne, Shehla; Posey, Isadora et al. (2009) 3,3'-diindolylmethane induction of p75NTR-dependent cell death via the p38 mitogen-activated protein kinase pathway in prostate cancer cells. Cancer Prev Res (Phila Pa) 2:566-71