The Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network (NRN) is a cooperative group of academic centers that perform multicenter clinical trials to investigate problems in neonatal medicine, particularly those related to prematurity and low birth weight. The advancement of neonatal care is facilitated through the network of academic centers that can study the required number of subjects to answer questions far more rapidly than individual centers acting alone. Cincinnati Children's Hospital Medical Center is nationally recognized as a leader in pediatric healthcare, with a reputation for excellence in patient care, research and medical education. The Cincinnati Children's Perinatal Institute provides newborn services to 27,000 newborns annually in the greater Cincinnati region, ensuring a consistent referral pattern and ability to provide population-based care. Since 1991, Cincinnati Children's has had continuous funding and has made significant contributions to the Neonatal Research Network because of the large patient population available for studies, state-of-the-art clinical and research facilities and clinical research infrastructure, strong investigators with extensive clinial research expertise, and excellent research support staff. During the next funding cycle, Cincinnati Children's will actively contribute a large number of subjects to all observational and clinical trials conducted by the NRN with meticulous execution of all research activities, including high levels of retention in follow-up. Cincinnati will also contribute to the scientific mission of the NRN through active engagement in the development of innovative research protocols designed to address important clinical questions in neonatology. Cincinnati Children's is also well positioned for the future with a wealth of seasoned clinical and translational investigators and a cadre of young investigators under their mentorship.

Public Health Relevance

The Eunice Kennedy Shriver NICHD Neonatal Research Network has advanced the field of neonatal medicine through well-designed clinical trials of agents and management strategies to improve short and long-term outcomes in infants and through observational studies where little or no evidence is available for clinical management.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Clinical Research Cooperative Agreements - Single Project (UG1)
Project #
5UG1HD027853-28
Application #
9462184
Study Section
Special Emphasis Panel (ZHD1)
Program Officer
Bremer, Andrew
Project Start
1991-04-01
Project End
2021-03-31
Budget Start
2018-04-01
Budget End
2019-03-31
Support Year
28
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Merhar, Stephanie L; McAllister, Jennifer M; Wedig-Stevie, Kathryn E et al. (2018) Retrospective review of neurodevelopmental outcomes in infants treated for neonatal abstinence syndrome. J Perinatol 38:587-592
Autmizguine, Julie; Tan, Sylvia; Cohen-Wolkowiez, Michael et al. (2018) Antifungal Susceptibility and Clinical Outcome in Neonatal Candidiasis. Pediatr Infect Dis J 37:923-929
Meyers, J M; Tan, S; Bell, E F et al. (2018) Neurodevelopmental outcomes among extremely premature infants with linear growth restriction. J Perinatol :
Phelps, Dale L; Watterberg, Kristi L; Nolen, Tracy L et al. (2018) Effects of Myo-inositol on Type 1 Retinopathy of Prematurity Among Preterm Infants <28 Weeks' Gestational Age: A Randomized Clinical Trial. JAMA 320:1649-1658
Reed, Benjamin D; Schibler, Kurt R; Deshmukh, Hitesh et al. (2018) The Impact of Maternal Antibiotics on Neonatal Disease. J Pediatr 197:97-103.e3
Srinivasan, Lakshmi; Page, Grier; Kirpalani, Haresh et al. (2017) Genome-wide association study of sepsis in extremely premature infants. Arch Dis Child Fetal Neonatal Ed 102:F439-F445
Watterberg, K L; Fernandez, E; Walsh, M C et al. (2017) Barriers to enrollment in a randomized controlled trial of hydrocortisone for cardiovascular insufficiency in term and late preterm newborn infants. J Perinatol 37:1220-1223
Di Fiore, Juliann M; Martin, Richard J; Li, Hong et al. (2017) Patterns of Oxygenation, Mortality, and Growth Status in the Surfactant Positive Pressure and Oxygen Trial Cohort. J Pediatr 186:49-56.e1
Jensen, Erik A; Dysart, Kevin C; Gantz, Marie G et al. (2017) Association between Use of Prophylactic Indomethacin and the Risk for Bronchopulmonary Dysplasia in Extremely Preterm Infants. J Pediatr 186:34-40.e2
Denson, Lee A; McDonald, Scott A; Das, Abhik et al. (2017) Early Elevation in Interleukin-6 is Associated with Reduced Growth in Extremely Low Birth Weight Infants. Am J Perinatol 34:240-247

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