It is postulated that the resolution of the problem of ethnic disparities in the burden of cardiovascular diseases will require a concerted, multi-disciplinary approach that includes investigators and practitioners dedicated to serving ethnic populations within their communities. This proposal seeks to establish a community-oriented Cardiovascular Disease Preventive Intervention Research Program (CPIP) at the Morehouse School of Medicine (MSM). This program is an essential step towards establishing a comprehensive research center of excellence in cardiovascular science that achieves the inter-disciplinary integration of basic science, clinical investigation and population-based research that is necessary to redress the problem of ethnic disparities in cardiovascular health. The long-term scientific objectives of the proposed program are two-fold: 1) to discover the etiologic basis for ethnic and geographic disparities in cardiovascular disease in the United States and 2) to pursue research that generates innovative, community-based preventive intervention programs that will reduce or eliminate these disparities. A complementary educational objective of the CPIP is to nurture the development of the next generation of cardiovascular investigators with a particular emphasis on expanding the ethnic and gender diversity of the research community. The primary objective of Phase I is to recruit a Program Director of the CPIP with a track record of scientific excellence in population-based cardiovascular science.
The specific aims of Phase I are: To establish the administrative and search committee structure necessary to implement an effective recruitment plan for the CPIP Program Director. To establish an External Advisory Board composed of scientific leaders in cardiovascular research that will provide consultative input on the programmatic development of the CPIP and identification of the CPIP Program Director. To enhance a novel integrative approach to cardiovascular disease-related research by facilitating institution-wide, multi-disciplinary research collaborations within the MSM community as well as our regional partners.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
HBCU Research Scientist Award (UH1)
Project #
5UH1HL073461-05
Application #
7324831
Study Section
Special Emphasis Panel (ZHL1-CSR-R (F1))
Program Officer
Paltoo, Dina
Project Start
2003-05-15
Project End
2010-11-30
Budget Start
2007-12-01
Budget End
2008-11-30
Support Year
5
Fiscal Year
2008
Total Cost
$710,000
Indirect Cost
Name
Morehouse School of Medicine
Department
Type
DUNS #
102005451
City
Atlanta
State
GA
Country
United States
Zip Code
30310
Riestra, Pia; Gebreab, Samson Y; Xu, Ruihua et al. (2017) Circadian CLOCK gene polymorphisms in relation to sleep patterns and obesity in African Americans: findings from the Jackson heart study. BMC Genet 18:58
Davis, Sharon K; Xu, Ruihua; Riestra, Pia et al. (2016) Association of adiponectin and socioeconomic status in African American men and women: the Jackson heart study. BMC Public Health 16:511
Davis, Sharon K; Xu, Ruihua; Gebreab, Samson Y et al. (2015) Association of ADIPOQ gene with type 2 diabetes and related phenotypes in African American men and women: the Jackson Heart Study. BMC Genet 16:147
Riestra, Pia; Gebreab, Samson Y; Xu, Ruihua et al. (2015) Gender-specific associations between ADIPOQ gene polymorphisms and adiponectin levels and obesity in the Jackson Heart Study cohort. BMC Med Genet 16:65
Davis, Sharon K; Gebreab, Samson Y; Xu, Ruihua et al. (2015) Association of adiponectin with type 2 diabetes and hypertension in African American men and women: the Jackson Heart Study. BMC Cardiovasc Disord 15:13
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Bidulescu, Aurelian; Liu, Jiankang; Chen, Zhimin et al. (2013) Associations of adiponectin and leptin with incident coronary heart disease and ischemic stroke in african americans: the jackson heart study. Front Public Health 1:16
Bidulescu, Aurelian; Liu, Jiankang; Hickson, DeMarc A et al. (2013) Gender differences in the association of visceral and subcutaneous adiposity with adiponectin in African Americans: the Jackson Heart Study. BMC Cardiovasc Disord 13:9
Yaghootkar, Hanieh; Lamina, Claudia; Scott, Robert A et al. (2013) Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes 62:3589-98
Bidulescu, Aurelian; Liu, Jiankang; Musani, Solomon K et al. (2011) Association of adiponectin with left ventricular mass in blacks: the Jackson Heart Study. Circ Heart Fail 4:747-53

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