The Johns Hopkins Institute for Clinical and Translational Research (ICTR) is dedicated to creating a new model for conducting clinical and translational research throughout the Johns Hopkins University, by addressing critical obstacles that impede the progress of basic science discoveries to the clinic, clinical discoveries into the community and results back to the research community. To propel additional high impact and efficient translational research, the ICTR will create Translational Research Communities and The Studio. Three Translational Research Communities will be organized around: 1) drugs, biologies, vaccines and devices; 2) biomarkers and diagnostic tests and 3) behavioral, social and systems interventions. These communities of researchers will help prioritize important clinical problems, develop new technologies and methodologies, support junior investigators, work with translational partners outside of Johns Hopkins, and promote efficient research. The Studio is both a place and a process by which research teams can present problems and get integrated, efficient, multidisciplinary consultations from multiple experts. With the emergence of complex big data originating from genomic as well as electronic health records, the ICTR has expanded the Quantitative Methodologies and Informatics Cores to create an integrated platform of data services. These new programs will assist our multiple research teams across the University to access a large array of services provided in five ICTR Cores: Translational Science, Human Subjects Research, Quantitative Methodology, Informatics and Research Participant and Community Partnership. Translational research is changing with more ambitious goals and access to more tools. Johns Hopkins University will continue to provide rigorous, comprehensive training to learners that range from graduate students, fellows, and junior faculty to practicing physicians so they are able to lead and work effectively in translational research teams. Through these innovative and comprehensive programs, the ICTR wants to lead Johns Hopkins University to be an exceptional engine of discovery and innovation.

Public Health Relevance

By identifying and overcoming barriers in the translational pathway, increasing scientific collaboration, providing consultative services, clinical infrastructure, and technology cores that bridge the gap between the laboratory and the clinic, the ICTR helps to speed the pace of scientific discovery, and bring effective therapies to the public, and improve the health of Americans.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
5UL1TR001079-03
Application #
8889744
Study Section
Special Emphasis Panel (ZAI1-PTM-C (S2))
Program Officer
Brazhnik, Olga
Project Start
2013-09-26
Project End
2018-04-30
Budget Start
2015-05-01
Budget End
2016-04-30
Support Year
3
Fiscal Year
2015
Total Cost
$12,911,237
Indirect Cost
$2,278,633
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205
Ramos, Juan C; Sparano, Joseph A; Rudek, Michelle A et al. (2018) Safety and Preliminary Efficacy of Vorinostat With R-EPOCH in High-risk HIV-associated Non-Hodgkin's Lymphoma (AMC-075). Clin Lymphoma Myeloma Leuk 18:180-190.e2
Talluri, Rajesh; Shete, Sanjay (2018) An approach to estimate bidirectional mediation effects with application to body mass index and fasting glucose. Ann Hum Genet 82:396-406
Inker, Lesley A; Grams, Morgan E; Levey, Andrew S et al. (2018) Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium. Am J Kidney Dis :
Togias, Alkis; Gergen, Peter J; Hu, Jack W et al. (2018) Rhinitis in children and adolescents with asthma: Ubiquitous, difficult to control, and associated with asthma outcomes. J Allergy Clin Immunol :
Al Rifai, Mahmoud; Greenland, Philip; Blaha, Michael J et al. (2018) Factors of health in the protection against death and cardiovascular disease among adults with subclinical atherosclerosis. Am Heart J 198:180-188
Rao, Vishal N; Zhao, Di; Allison, Matthew A et al. (2018) Adiposity and Incident Heart Failure and its Subtypes: MESA (Multi-Ethnic Study of Atherosclerosis). JACC Heart Fail 6:999-1007
Vella, Chantal A; Cushman, Mary; Van Hollebeke, Rachel B et al. (2018) Associations of Abdominal Muscle Area and Radiodensity with Adiponectin and Leptin: The Multiethnic Study of Atherosclerosis. Obesity (Silver Spring) 26:1234-1241
Simner, Patricia J; Johnson, J Kristie; Brasso, William B et al. (2018) Multicenter Evaluation of the Modified Carbapenem Inactivation Method and the Carba NP for Detection of Carbapenemase-Producing Pseudomonas aeruginosa and Acinetobacter baumannii. J Clin Microbiol 56:
Porter, Kathryn M; Danis, Marion; Taylor, Holly A et al. (2018) Defining the Scope and Improving the Quality of Clinical Research Ethics Consultation: Response to Open Peer Commentaries About the National Collaborative. Am J Bioeth 18:W13-W15
Thakur, Kiran T; Vareta, Jimmy; Carson, Kathryn A et al. (2018) Cerebrospinal fluid Plasmodium falciparum histidine-rich protein-2 in pediatric cerebral malaria. Malar J 17:125

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