The mission of Spectrum, the CTSA-supported independent research center at Stanford, is to transform the academic enterprise to optimally support clinical and translational research and education (CTRE). Spectrum's programs are designed to extend from the earliest phase of basic discovery to final implementation of these discoveries in the population. The ultimate goals of our efforts are to streamline the translation of basic innovations into practical solutions that maintain and improve human health, and to educate the next generation of CTR leaders. In the next five years. Spectrum will leverage institutional strengths to nurture our entrepreneurial researchers to efficiently transfer discoveries from the laboratory to the bedside and into the community. The CTSA will provide critical resources, services and educational opportunities to ensure progress toward this mission.
The specific aims of Spectrum are: 1) Educate the next generation of investigators with the multidisciplinary skills required to conduct cutting- edge clinical and translational research to meet the opportunities and challenges of medicine in the 21st century. Spectrum will facilitate the transformation of medical research training from a narrow focus on discipline-restricted expertise to a more interdisciplinary team approach where trainees become conversant in the language, processes and tools used across the full extent of the translational pipeline (T1-T4). 2) Create an institutional home conducive to efficiently translating the most innovative discoveries made by our basic, translational and clinical scientists into products and processes that directly improve human health and well-being. Spectrum will provide the institutional environment to identify and then support those discoveries that are most ready for translation. 3) Develop and implement CTRE resources and services to accelerate the translation of discoveries into better human health, while simultaneously reducing operating costs. Spectrum will ensure that investigators receive the necessary clinical trial, informatics, statistics, regulatory, ethics and administrative support to maximize their research productivity, and optimize the participation of diverse populations.

Public Health Relevance

The mission of Spectrum, Stanford's CTSA-supported center, is to transform the enterprise to best support discovery, innovation and education in clinical and translational research across the university. Spectrum's programs extend from the earliest phase of basic discovery to final implementation in the population, with an ultimate goal of strengthening healthcare and improving cost efficiencies.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
5UL1TR001085-02
Application #
8743340
Study Section
Special Emphasis Panel (ZAI1-PTM-C (S2))
Program Officer
Wilson, Todd
Project Start
2013-09-26
Project End
2018-04-30
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
2
Fiscal Year
2014
Total Cost
$8,460,470
Indirect Cost
$2,980,697
Name
Stanford University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
Haller, Michael J; Schatz, Desmond A; Skyler, Jay S et al. (2018) Low-Dose Anti-Thymocyte Globulin (ATG) Preserves ?-Cell Function and Improves HbA1c in New-Onset Type 1 Diabetes. Diabetes Care 41:1917-1925
Porter, Kathryn M; Danis, Marion; Taylor, Holly A et al. (2018) The Emergence of Clinical Research Ethics Consultation: Insights From a National Collaborative. Am J Bioeth 18:39-45
Jelliffe-Pawlowski, Laura L; Rand, Larry; Bedell, Bruce et al. (2018) Prediction of preterm birth with and without preeclampsia using mid-pregnancy immune and growth-related molecular factors and maternal characteristics. J Perinatol 38:963-972
Liu, Qing; Van Bortle, Kevin; Zhang, Yue et al. (2018) Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid. Sci Rep 8:12960
Piester, Travis; Frymoyer, Adam; Christofferson, Megan et al. (2018) A Mobile Infliximab Dosing Calculator for Therapy Optimization in Inflammatory Bowel Disease. Inflamm Bowel Dis 24:227-234
Hamad, Rita; Elser, Holly; Tran, Duy C et al. (2018) How and why studies disagree about the effects of education on health: A systematic review and meta-analysis of studies of compulsory schooling laws. Soc Sci Med 212:168-178
Chen, Lang; Bae, Se Ri; Battista, Christian et al. (2018) Positive Attitude Toward Math Supports Early Academic Success: Behavioral Evidence and Neurocognitive Mechanisms. Psychol Sci 29:390-402
Kim, Jinkyung; Xia, Anping; Grillet, Nicolas et al. (2018) Osmotic stabilization prevents cochlear synaptopathy after blast trauma. Proc Natl Acad Sci U S A 115:E4853-E4860
Mao, Qingqing; Jay, Melissa; Hoffman, Jana L et al. (2018) Multicentre validation of a sepsis prediction algorithm using only vital sign data in the emergency department, general ward and ICU. BMJ Open 8:e017833
Johnston, Emily E; Alvarez, Elysia; Saynina, Olga et al. (2018) Inpatient utilization and disparities: The last year of life of adolescent and young adult oncology patients in California. Cancer 124:1819-1827

Showing the most recent 10 out of 406 publications