The Indiana Clinical and Translational Sciences Institute (CTSl) was created in 2008 at the crest of a wave of transfornnation of the three research universities in Indiana and has become a flagship catalyst for the state's biomedical initiatives. The mission of the Indiana CTS! is to be an integrated home for clinical and translational research that creates a shared, investigator-friendly institutional environment and provides easily accessible resources, services, and training to conduct the highest-quality research dedicated to improving human health across Indiana and beyond. The Four Specific Aims of the Indiana CTSl are:
Aim 1. Implement an Indiana roadmap for building the ideal research environment and collaborative platforms to conduct innovative research using our excellent multi-institutional, public-private partnerships throughout the state of Indiana and beyond by bringing together all three major research universities, Indiana, Purdue and Notre Dame, the state's key health care provider partners, private sector and corporate entities, and local and state agencies to create the infrastructure.
Aim 1 1. Further develop our successful Indiana CTSl established with the previous award into an """"""""integrated home"""""""" that supports the careers and research projects of translational scientists and trainees through a streamlined structure, empowered leadership and administration, coordinated partner institution resources, robust informatics infrastructure, innovative project development teams, and continuous evaluation and process improvemenL Aim Ml. Promote utilization of our innovative services and a well-tested network of resources and technologies in order to catalyze high-quality, efficient, and safe clinical and translational research. We have created Project Assistance and Resources for Translational Scientists (PARTS) suite of both established and new research support services and resources, a statewide network of technology cores, and a coordinated human subject research services and facilities.
Aim I V. Extend our success in statewide education and training of clinical and translational research workforce through our Career development. Education and Research Training (CERT) suite of programs that includes successful existing programs, new training programs, and novel educational tools.

Public Health Relevance

The Indiana Clinical and Translational Sciences Institute (CTSl) was created in 2008 as a statewide institute by the partnership of three research universities in Indiana (Indiana, Purdue and Notre Dame) and has become an essential resource for the state's biomedical initiatives. Here we describe its innovative vision, its impact, and its success in creating public-private partnerships to benefit the health and economy of the state.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
5UL1TR001108-02
Application #
8743351
Study Section
Special Emphasis Panel (ZAI1)
Program Officer
Wilson, Todd
Project Start
2013-09-26
Project End
2018-04-30
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
2
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Psychiatry
Type
Schools of Medicine
DUNS #
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
RISE Consortium (2018) Metabolic Contrasts Between Youth and Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes: II. Observations Using the Oral Glucose Tolerance Test. Diabetes Care 41:1707-1716
Miller, Jason E; Shivakumar, Manu K; Risacher, Shannon L et al. (2018) Codon bias among synonymous rare variants is associated with Alzheimer's disease imaging biomarker. Pac Symp Biocomput 23:365-376
O'Haire, Marguerite E; Rodriguez, Kerri E (2018) Preliminary efficacy of service dogs as a complementary treatment for posttraumatic stress disorder in military members and veterans. J Consult Clin Psychol 86:179-188
Bell, Teresa M; Vetor, Ashley N; Zarzaur, Ben L (2018) Prevalence and treatment of depression and posttraumatic stress disorder among trauma patients with non-neurological injuries. J Trauma Acute Care Surg 85:999-1006
Yu, Qilin; Li, Jing; Murrell, Michael P et al. (2018) Balance between Force Generation and Relaxation Leads to Pulsed Contraction of Actomyosin Networks. Biophys J 115:2003-2013
Quirin, Kayla A; Kwon, Jason J; Alioufi, Arafat et al. (2018) Safety and Efficacy of AAV Retrograde Pancreatic Ductal Gene Delivery in Normal and Pancreatic Cancer Mice. Mol Ther Methods Clin Dev 8:8-20
Dai, Chen; Arceo, Jennifer; Arnold, James et al. (2018) Metabolomics of oncogene-specific metabolic reprogramming during breast cancer. Cancer Metab 6:5
Xiang, Anny H; Trigo, Enrique; Martinez, Mayra et al. (2018) Impact of Gastric Banding Versus Metformin on ?-Cell Function in Adults With Impaired Glucose Tolerance or Mild Type 2 Diabetes. Diabetes Care 41:2544-2551
Luther, Lauren; Coffin, George M; Firmin, Ruth L et al. (2018) A test of the cognitive model of negative symptoms: Associations between defeatist performance beliefs, self-efficacy beliefs, and negative symptoms in a non-clinical sample. Psychiatry Res 269:278-285
Langer, Kirstin B; Ohlemacher, Sarah K; Phillips, M Joseph et al. (2018) Retinal Ganglion Cell Diversity and Subtype Specification from Human Pluripotent Stem Cells. Stem Cell Reports 10:1282-1293

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