The major objective of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) is to gather the data needed to estimate the prevalence and incidence of alcohol use disorders and their associated disabilities in the U.S. general population. This information will allow for the examination of the natural history of alcohol use disorders and their associated disabilities, identification of subgroups of the population at risk for these disabilities, refinement of etiologic hypotheses, and formation of the basis of rational and scientifically-based intervention and prevention programs. NESARC is a longitudinal survey with its first wave conducted in 2001-2002. The second wave entered the field in September 2004. The NESARC is a representative sample of the United States population, and 43,093 Americans participated in Wave 1. During Wave 2, an attempt to interview all 43,093 respondents will be made. The target population of the NESARC is the non-institutionalized population, 18 years and older, residing in the United States and the District of Columbia in households and selected group quarters. In Wave 3 of the NESARC, major consideration will be given to the collection of DNA. A public use database of the Wave 1 NESARC was disseminated to the research community in June 2004, and timely disposition of public use databases for subsequent NESARC waves also will follow. The major objectives of the Wave 1 and Wave 2 NESARC are: -to determine the prevalence, remission, chronicity and recurrence of alcohol and drug use disorders and their associated psychiatric and medical comorbidities; -to understand the relationships between alcohol and drug use disorders and other psychiatric and medical disorders over time; -to determine the number and characteristics of individuals receiving and in need of treatment for alcohol and drug use disorders and their associated disabilities; -to increase understanding of the interrelationships among individual and environmental factors, conditions and situations under which alcohol and violence are connected; -to determine the magnitude and extent of binge drinking among college-aged young adults and the adult population and to identify the characteristics of binge drinkers and risk factors influencing the initiation and remission of this hazardous drinking pattern; -to test competing etiologic models of comorbidity within a longitudinal context; -to conduct methodological and nosological research for the purpose of creating DSM-IV/ICD-11 research diagnostic criteria, as an adjunct to their clinical diagnostic criteria, for use in research areas (e.g., genetics, neuroscience) that have been hindered by existing clinical criteria; -to estimate the disease burden (DALYs and YLDs) attributable to alcohol, drug and mental disorders in the United States; and -to advance knowledge of the gene-environment interaction as it contributes to alcohol abuse and dependence and their associated medical and psychiatric comorbidities.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Intramural Research (Z01)
Project #
1Z01AA000449-02
Application #
7146680
Study Section
(LEB)
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
2005
Total Cost
Indirect Cost
Name
Alcohol Abuse and Alcoholism
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Mackenzie, Corey S; Reynolds, Kristin; Cairney, John et al. (2012) Disorder-specific mental health service use for mood and anxiety disorders: associations with age, sex, and psychiatric comorbidity. Depress Anxiety 29:234-42
Lopez-Quintero, Catalina; Perez de los Cobos, Jose; Hasin, Deborah S et al. (2011) Probability and predictors of transition from first use to dependence on nicotine, alcohol, cannabis, and cocaine: results of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). Drug Alcohol Depend 115:120-30
Comer, Jonathan S; Blanco, Carlos; Hasin, Deborah S et al. (2011) Health-related quality of life across the anxiety disorders: results from the national epidemiologic survey on alcohol and related conditions (NESARC). J Clin Psychiatry 72:43-50
Weinstock, Lauren M; Strong, David; Uebelacker, Lisa A et al. (2009) Differential item functioning of DSM-IV depressive symptoms in individuals with a history of mania versus those without: an item response theory analysis. Bipolar Disord 11:289-97
Sareen, Jitender; Pagura, Jina; Grant, Bridget (2009) Is intimate partner violence associated with HIV infection among women in the United States? Gen Hosp Psychiatry 31:274-8
Dawson, Deborah A; Li, Ting-Kai; Chou, S Patricia et al. (2009) Transitions in and out of alcohol use disorders: their associations with conditional changes in quality of life over a 3-year follow-up interval. Alcohol Alcohol 44:84-92
Hatzenbuehler, Mark L; Keyes, Katherine M; Narrow, William E et al. (2008) Racial/ethnic disparities in service utilization for individuals with co-occurring mental health and substance use disorders in the general population: results from the national epidemiologic survey on alcohol and related conditions. J Clin Psychiatry 69:1112-21
Pietrzak, Robert H; Morasco, Benjamin J; Blanco, Carlos et al. (2007) Gambling level and psychiatric and medical disorders in older adults: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Am J Geriatr Psychiatry 15:301-13
Blanco, Carlos; Alderson, Donald; Ogburn, Elizabeth et al. (2007) Changes in the prevalence of non-medical prescription drug use and drug use disorders in the United States: 1991-1992 and 2001-2002. Drug Alcohol Depend 90:252-60
Grant, Bridget F; Harford, Thomas C; Muthen, Bengt O et al. (2007) DSM-IV alcohol dependence and abuse: further evidence of validity in the general population. Drug Alcohol Depend 86:154-66

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