A pharmacological approach to remedy physiological declines associated with normal aging is desirable from the standpoint of minimizing the economic and sociological costs of an aging population. However, identifying and characterizing compounds that improve performance in the elderly is expensive and time-consuming. This project aims to quickly identify lead compounds that improve function in old age by using the nematode, C. elegans, to rapidly screen candidate compounds. Current work is focused on characterizing the effects of two types of antioxidant compounds on the nematode's aging process.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Intramural Research (Z01)
Project #
1Z01AG000322-01
Application #
6815146
Study Section
(LN)
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
2003
Total Cost
Indirect Cost
Name
Aging
Department
Type
DUNS #
City
State
Country
United States
Zip Code