(1) Both passive and active immunity against experimental cryptococcosis could be induced in mice by a vaccine composed of crytococcal capsular polysaccharide conjugated to tetanus toxoid. (2) Candida albicans maltase has been purified and the gene cloned and sequenced. (3) Cryptococcus neoformans diphenol oxidase has been released from the cell wall and partially purified. (4) The small subunit ribosomal RNA of Blastomyces dermatitides has been cloned and sequenced. (5) An integrin like protein has been found on the surface of C. albicans.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Intramural Research (Z01)
Project #
1Z01AI000043-26
Application #
3803079
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
26
Fiscal Year
1991
Total Cost
Indirect Cost
City
State
Country
United States
Zip Code