A vaccine against HIV would provide a simple, low-cost means of controlling the spread of AIDS worldwide, particularly in the developing world where other treatments are unavailable. This research study aims to improve immunogenicity of HIV vaccines by selective mutation of HIV proteins and development of effective adjuvants. Promising candidates are being tested in both animal studies and human clinical trials.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Intramural Research (Z01)
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