Abstract

Residents contribute to the clinical research program of the NCI and the NIH. In the past year residents residents have been primary authors or co-authors on more than 10 publications, on a diversity of topics including 1) myocardial changes in patients receiving IL-2 immmunotherapy, 2) antigenic changes in malignant melanoma, 3) proteomic approaches to the diagnosis of graft vs. host disease, 4) the pathology of Fabry's disease as altered by enzyme replacement therapy, 5) new substrates for protein detection in protein microarrays, and 6) surgical pathology in the era of the Civil War. Through their efforts as anatomic pathology residents in training, they help illuminate the pathological changes associated with cancer therapy, and explore new techniques to improve cancer diagnosis.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Division of Basic Sciences - NCI (NCI)
Type
Intramural Research (Z01)
Project #
1Z01BC010684-02
Application #
7338782
Study Section
(LP)
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
2006
Total Cost
Indirect Cost

  Institution

Name
Basic Sciences
Department
Type
DUNS #
City
State
Country
United States
Zip Code

  Publications

Geho, David H; Killian, J Keith; Nandi, Animesh et al. (2007) Fluorescence-based analysis of cellular protein lysate arrays using quantum dots. Methods Mol Biol 374:229-37
Srinivasan, Ramaprasad; Daniels, Jasmine; Fusaro, Vincent et al. (2006) Accurate diagnosis of acute graft-versus-host disease using serum proteomic pattern analysis. Exp Hematol 34:796-801
Ingkanisorn, W Patricia; Paterson, D Ian; Calvo, Katherine R et al. (2006) Cardiac magnetic resonance appearance of myocarditis caused by high dose IL-2: similarities to community-acquired myocarditis. J Cardiovasc Magn Reson 8:353-60
Politei, Juan (2006) Schiffmann R, Rapkiewicz A, Abu-Asab M, Ries M, Askari H, Tsokos M, Quezado M. Pathological findings in a patient with Fabry disease, who died after 2.5 years of enzyme replacement. Virchows Arch. 2005 Nov 29; 1-7. Virchows Arch 448:873
Fountaine, Thomas J; Wincovitch, Stephen M; Geho, David H et al. (2006) Multispectral imaging of clinically relevant cellular targets in tonsil and lymphoid tissue using semiconductor quantum dots. Mod Pathol 19:1181-91
Schiffmann, Raphael; Rapkiewicz, Amy; Abu-Asab, Mones et al. (2006) Pathological findings in a patient with Fabry disease who died after 2.5 years of enzyme replacement. Virchows Arch 448:337-43
Rapkiewicz, Amy V; Hawk, Alan; Noe, Adrienne et al. (2005) Surgical pathology in the era of the Civil War: the remarkable life and accomplishments of Joseph Janvier Woodward, MD. Arch Pathol Lab Med 129:1313-6
Gulmann, Christian; Espina, Virginia; Petricoin 3rd, Emanuel et al. (2005) Proteomic analysis of apoptotic pathways reveals prognostic factors in follicular lymphoma. Clin Cancer Res 11:5847-55
Feldman, Andrew L; Berthold, Frank; Arceci, Robert J et al. (2005) Clonal relationship between precursor T-lymphoblastic leukaemia/lymphoma and Langerhans-cell histiocytosis. Lancet Oncol 6:435-7
Aisner, Dara L; Maker, Ajay; Rosenberg, Steven A et al. (2005) Loss of S100 antigenicity in metastatic melanoma. Hum Pathol 36:1016-9

Showing the most recent 10 out of 16 publications