1. OBJECTIVES/METHODS : Bleed vaccinees annually; test serum for rabies-- neutralizing antibody by the Rapid Fluorescent Focus Inhibition Test (RFFIT), boost those with less than 1.0 International Unit rabies-neutralizing antibody/ml serum with HDCS Rabies Vaccine (Institut Merieux). 2. RESULTS: Distribution of human serum quantified for rabies-neutralizing antibody in IU/ml: Employing Agency (serum source) Number RFFIT Tests CBER-FDA 60 NIH 70 Maryland Department of Agriculture 20 (Frederick, MD) TOTAL HUMAN SERUM TESTS 150

Agency
National Institute of Health (NIH)
Institute
Food and Drug Administration (FDA)
Type
Intramural Research (Z01)
Project #
1Z01BE003002-09
Application #
3811232
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
9
Fiscal Year
1990
Total Cost
Indirect Cost