Direct quantitation of revertants in samples of oral poliovirus vaccine (OPV) was found to be a useful tool for consistency monitoring of OPV production, and was introduced as a mandatory test during OPV production and control. We will use the same approach for development of similar methods for control of other live viral vaccines, e.g., live mumps vaccine and yellow fever vaccine.

Agency
National Institute of Health (NIH)
Institute
Food and Drug Administration (FDA)
Type
Intramural Research (Z01)
Project #
1Z01BR005005-02
Application #
6161398
Study Section
Special Emphasis Panel (LMD)
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1997
Total Cost
Indirect Cost