This work investigates procedures for testing equivalence and estimating the ratio of marginal probabilities for paired dichotomous variables. A procedure is developed for conducting a test of equivalence and finding a confidence interval for the ratio of probabilities. This is appropriate when there is no gold standard of disease. A 2 d.f. chi-squared test is developed for the case in which a gold standard exists. These are both extensions of McNemar's test for paired dichotomous data.

Agency
National Institute of Health (NIH)
Institute
Food and Drug Administration (FDA)
Type
Intramural Research (Z01)
Project #
1Z01BS001003-01
Application #
5200885
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Division of Biologics Standards
Department
Type
DUNS #
City
State
Country
United States
Zip Code