Using M-mode echocardiography, an estimate of left ventricular filling pressure in critically ill patients was calculated by determining the ratio of the time the onset of the QRS complex on EKG to mitral valve closure and the time from aortic valve closure to mitral valve E-point. Using linear regression, an equation was derived that provided an estimate of pulmonary capillary wedge pressure. This estimate was compared to the pulmonary capillary wedge pressure measured by standard techniques using a pulmonary artery catheter, and a strong correlation was found. Serial studies in individual patients showed a good correlation of echo-determined pulmonary capillary wedge pressure with pulmonary artery catheter-determined pressure may allow some patients to be managed with a shorter duration of pulmonary artery catheterization and may decrease the need for repeated catheterization in some patients.

Agency
National Institute of Health (NIH)
Institute
Clinical Center (CLC)
Type
Intramural Research (Z01)
Project #
1Z01CL000006-04
Application #
3939379
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Clinical Center
Department
Type
DUNS #
City
State
Country
United States
Zip Code