Daily serial echocardiograms are done on patients with septic shock to evaluate left ventricular size and function. Studies using radionuclide cineangiography and simultaneous hemodynamic measurements have demonstrated a reversible depression of left ventricular dilatation. However, because of the risks associated with ionizing radiation, repeated radionuclide studies cannot be performed frequently. Echocardiography is a noninvasive technique which can be performed daily (or more frequently if necessary). By obtaining frequent echocardiograms, the time course of the changes in ventricular size and function which occur in patients with septic shock can be better defined. In addition, regional wall motion abnormalities can be better detected using echocardiography with multiple views than with radionuclide cineangiography using a single view. Serial echocardiography has also demonstrated the same reversible changes in myocardial size and function demonstrated by radionuclide cineangiography, thus confirming these findings by an independent technique.

Agency
National Institute of Health (NIH)
Institute
Clinical Center (CLC)
Type
Intramural Research (Z01)
Project #
1Z01CL000028-03
Application #
3916456
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Clinical Center
Department
Type
DUNS #
City
State
Country
United States
Zip Code