The objective of this drug interaction study in HIV-infected patients is to characterize the pharmacokinetics of stavudine when given alone and in combination with three drugs commonly used to manage opportunistic infections. Ten patients have completed the study. The treatments were well tolerated with minimal adverse effects. Data analysis is currently ongoing. Results are expected in the last quarter of 1996.

Agency
National Institute of Health (NIH)
Institute
Clinical Center (CLC)
Type
Intramural Research (Z01)
Project #
1Z01CL000102-01
Application #
2456657
Study Section
Pharmacy Review Committee (PHAR)
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Clinical Center
Department
Type
DUNS #
City
State
Country
United States
Zip Code