Pharmacokinetics of theophylline in healthy elderly were compared to that in a control young group to assess the effect of age on its absorption and disposition. Four elderly and 6 young subjects have been studied. No age related differences in theophylline kinetic parameter values were found. These data suggest that theophylline dosage need not be altered in the elderly based on age alone.

Agency
National Institute of Health (NIH)
Institute
Clinical Center (CLC)
Type
Intramural Research (Z01)
Project #
1Z01CL005058-01
Application #
4691994
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Clinical Center
Department
Type
DUNS #
City
State
Country
United States
Zip Code