There are many viruses which may cause respiratory infections in the normal and immunocompromised host. This study looks at the cystic fibrosis patient to determine the incidence of respiratory viral disease in the group, and, more specifically examining CF patients undergoing or about to undergo gene therapy, are there viruses present which might interfere with using a replication-deficient adenovirus vector as the gene therapy modality. Bronchial lavages and brushings and nasal brushings will be collected and cultured by the vial assay for the detections of herpes simplex virus, cytomegalovirus, varicella-zoster virus, respiratory syncytial virus, influenza virus, parainfluenza virus, and adenovirus.

Agency
National Institute of Health (NIH)
Institute
Clinical Center (CLC)
Type
Intramural Research (Z01)
Project #
1Z01CL010217-01
Application #
3774524
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Clinical Center
Department
Type
DUNS #
City
State
Country
United States
Zip Code