A project to develop the complete immunophenotype of memory B cell has been initiated. This is being done evaluating normal subjects and patients with a number of immune disorders. In addition, the immunophenotypic data is being compared with Ig gene recombination results generated in Dr. P. Lipskys laboratory (NIAMS).
Bleesing, Jack J H; Brown, Margaret R; Novicio, Cynthia et al. (2002) A composite picture of TcR alpha/beta(+) CD4(-)CD8(-) T Cells (alpha/beta-DNTCs) in humans with autoimmune lymphoproliferative syndrome. Clin Immunol 104:21-30 |