A number of HMBA analogs were synthesized and evaluated as differentiating agents in the in vitro HL-60 cell system. Several compounds were as effective and potent as HMBA but none were clearly superior.

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Treatment (NCI)
Type
Intramural Research (Z01)
Project #
1Z01CM003580-17
Application #
3963199
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
17
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Cancer Treatment
Department
Type
DUNS #
City
State
Country
United States
Zip Code