Abstract

The predominant activity of the section has been the continuing studies of families with specific types of cancer such as melanoma, nevoid basal cell carcinoma syndrome, ovarian cancer, chronic lymphocytic leukemia, and Hodgkin's disease. In addition, more traditional epidemiologic studies such as case- control and cohort studies of the etiology of lung cancer, cutaneous melanoma, and leukemia after ovarian cancer have continued. Most of these have had a biochemical component. A collaborative study of the risk of cancer related to dioxin exposure in Seveso, Italy, was begun. New initiatives include interdisciplinary studies of breast, prostate, bladder, and endometrial cancers, and a cohort study of leukemia following epipodophyllotoxin exposure.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Intramural Research (Z01)
Project #
1Z01CP004410-92
Application #
3838304
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
92
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
Division of Cancer Epidemiology and Genetics
Department
Type
DUNS #
City
State
Country
United States
Zip Code

  Publications

Goldin, Lynn R; McMaster, Mary L; Caporaso, Neil E (2013) Precursors to lymphoproliferative malignancies. Cancer Epidemiol Biomarkers Prev 22:533-9
Han, Summer S; Yeager, Meredith; Moore, Lee E et al. (2012) The chromosome 2p21 region harbors a complex genetic architecture for association with risk for renal cell carcinoma. Hum Mol Genet 21:1190-200
Brau-Javier, Cristina N; Gonzales-Chavez, Jose; Toro, Jorge R (2012) Chronic cutaneous pustulosis due to a 175-kb deletion on chromosome 2q13: excellent response to anakinra. Arch Dermatol 148:301-4
Kristinsson, Sigurdur Y; Goldin, Lynn R; Turesson, Ingemar et al. (2012) Familial aggregation of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia with solid tumors and myeloid malignancies. Acta Haematol 127:173-7
Goldin, Lynn R; Kristinsson, Sigurdur Y; Liang, Xueying Sharon et al. (2012) Familial aggregation of acute myeloid leukemia and myelodysplastic syndromes. J Clin Oncol 30:179-83
Lindqvist, Ebba K; Goldin, Lynn R; Landgren, Ola et al. (2011) Personal and family history of immune-related conditions increase the risk of plasma cell disorders: a population-based study. Blood 118:6284-91
Goldin, Lynn R; Lanasa, Mark C; Slager, Susan L et al. (2010) Common occurrence of monoclonal B-cell lymphocytosis among members of high-risk CLL families. Br J Haematol 151:152-8
Kristinsson, Sigurdur Y; Björkholm, Magnus; Goldin, Lynn R et al. (2009) Patterns of hematologic malignancies and solid tumors among 37,838 first-degree relatives of 13,896 patients with multiple myeloma in Sweden. Int J Cancer 125:2147-50
Bradford, Porcia T; Goldstein, Alisa M; McMaster, Mary L et al. (2009) Acral lentiginous melanoma: incidence and survival patterns in the United States, 1986-2005. Arch Dermatol 145:427-34
Kristinsson, Sigurdur Y; Koshiol, Jill; Goldin, Lynn R et al. (2009) Genetics- and immune-related factors in the pathogenesis of lymphoplasmacytic lymphoma/ Waldenström's macroglobulinemia. Clin Lymphoma Myeloma 9:23-6

Showing the most recent 10 out of 29 publications