Abstract

The Oswaldo Cruz Foundation (FIOCRUZ) Therapeutic and Prevention HIV/AIDS Clinical Trials Unit (FioTrials), is a multidisciplinary, integrated research consortium based in Rio de Janeiro, Brazil with two clinical research sites (CRS) located at the Institute de Pesquisa Clinica Evandro Chagas (IPEC CRS) and Hospital Geral de Nova Iguagu (HGNI CRS). Both sites offer routine clinical care for both """"""""at-risk"""""""" and HIV-infected persons and cater to the needs of certain disenfranchised populations, which include individuals who may be racial minorities, women, poverty stricken, uneducated, and/or substance abusers. As a whole, the FioTrials unit has unique strengths to offer the ACTG and HPTN networks, as an established and integrated unit leadership who is partnered with FIOCRUZ, a supportive research-driven institution, a participant population that complements the scientific agendas of both networks, and researchers with significant experience in the development of HIV/AIDS prevention and treatment strategies. ADMINISTRATIVE COMPONENT:

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project with Complex Structure Cooperative Agreement (UM1)
Project #
5UM1AI069476-05
Application #
8208878
Study Section
Special Emphasis Panel (ZAI1-BLG-A (M2))
Program Officer
Castillo, Blanca E
Project Start
2008-01-15
Project End
2012-12-31
Budget Start
2012-01-01
Budget End
2012-12-31
Support Year
5
Fiscal Year
2012
Total Cost
$2,088,387
Indirect Cost
$45,306

  Institution

Name
Fundacao Oswaldo Cruz
Department
Type
DUNS #
899294177
City
Rio de Janeiro
State
Country
Brazil
Zip Code
21040--360

  Publications

Barré-Sinoussi, Françoise; Abdool Karim, Salim S; Albert, Jan et al. (2018) Expert consensus statement on the science of HIV in the context of criminal law. J Int AIDS Soc 21:e25161
Costa, Jessica de Mattos; Torres, Thiago Silva; Coelho, Lara Esteves et al. (2018) Adherence to antiretroviral therapy for HIV/AIDS in Latin America and the Caribbean: Systematic review and meta-analysis. J Int AIDS Soc 21:
Jalil, Emilia M; Grinsztejn, Beatriz; Velasque, Luciane et al. (2018) Awareness, Willingness, and PrEP Eligibility Among Transgender Women in Rio de Janeiro, Brazil. J Acquir Immune Defic Syndr 79:445-452
Caro-Vega, Y; Belaunzarán-Zamudio, P F; Crabtree-Ramírez, B et al. (2018) Trends in proportion of older HIV-infected people in care in Latin America and the Caribbean: a growing challenge. Epidemiol Infect 146:1308-1311
Coelho, Lara; Rebeiro, Peter F; Castilho, Jessica L et al. (2018) Early Retention in Care Neither Mediates Nor Modifies the Effect of Sex and Sexual Mode of HIV Acquisition on HIV Survival in the Americas. AIDS Patient Care STDS 32:306-313
Caetano, Diogo Gama; Côrtes, Fernanda Heloise; Bello, Gonzalo et al. (2018) Next-generation sequencing analyses of the emergence and maintenance of mutations in CTL epitopes in HIV controllers with differential viremia control. Retrovirology 15:62
Bakal, David R; Coelho, Lara E; Luz, Paula M et al. (2018) Obesity following ART initiation is common and influenced by both traditional and HIV-/ART-specific risk factors. J Antimicrob Chemother 73:2177-2185
De Boni, Raquel B; Peratikos, Meridith B; Shepherd, Bryan E et al. (2018) Is substance use associated with HIV cascade outcomes in Latin America? PLoS One 13:e0194228
Adachi, Kristina; Xu, Jiahong; Ank, Bonnie et al. (2018) Congenital CMV and HIV Perinatal Transmission. Pediatr Infect Dis J :
Ngongondo, McNeil; Miyahara, Sachiko; Hughes, Michael D et al. (2018) Hepatotoxicity During Isoniazid Preventive Therapy and Antiretroviral Therapy in People Living With HIV With Severe Immunosuppression: A Secondary Analysis of a Multi-Country Open-Label Randomized Controlled Clinical Trial. J Acquir Immune Defic Syndr 78:54-61

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