Major efforts included: (1) Publishing an analysis of risk of lung cancer from radon and smoking and using this model to estimate risk attributable to radon in the U.S. and Germany; (2) publishing case- control data on risks from exposure to radon in homes and completing a pilot assessment of radon exposures in underground dwellings in Gansu, China; (3) publishing data from six cohorts that demonstrate persistent risk of thyroid cancer forty years after exposure; (4) completing validation studies to relate """"""""gold standard"""""""" personal dosimetry to other measurements of electromagnetic radiation; (5) publishing papers on the design, exposure assessment and gender differences in risk of hematopoietic disease following benzene exposure; (6) establishing dose- response relationships for bladder cancer from cyclophosphamide treatment for non-Hodgkin's lymphoma; (7) demonstrating increased levels of P45012A after ingestion of pan-fried meats and an inverse relation between P45012A blood levels and amounts of unmetabolized heterocyclic aromatic amines in urine; (8) showing that DNA ploidy adds little prognostic information in ovarian cancer; (9) showing that vitamin supplementation is associated with fewer strokes and lower blood pressure in men in an intervention trial in Linxian, China; (10) publishing two papers on a large-scale community intervention trial that show slightly increased rates of smoking cessation among light or moderate smokers but not among heavy smokers in intervention communities; (11) publishing data on survivors of childhood leukemia showing that those with cranial irradiation needed more special education training but graduated from high school at normal rates; (12) developing a model to project breast cancer that incorporates mammographic density, and devising convenient graphs for risk projection; (13) publishing attributable risk calculations for esophageal cancer in Shanghai, mesothelioma in the U.S. and stomach cancer in Northern Italy; (14) showing that rates of loss of CD4+ lymphocytes have not changed with calendar time of HIV infection; and (15) using back-calculation to estimate age-, race- and gender- specific prevalence and patterns of HIV in the U.S.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Intramural Research (Z01)
Project #
1Z01CP005498-10
Application #
5201498
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
10
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Division of Cancer Epidemiology and Genetics
Department
Type
DUNS #
City
State
Country
United States
Zip Code