Sweat was evaluated as a media for use in monitoring drug exposure of human subjects. Healthy subjects with a history of chemical substance abuse volunteered for these studies. Informed consent was obtained and all procedures were approved by the hospital Institutional Review Board. Following the administration of cocaine, marijuana or opiates, sweat samples were collected periodically. Other biological specimens like saliva, blood, urine and hair also were collected. Specimens were analyzed by immunoassay and gas chromatography/mass spectrometry. These data will provide new information on this unusual biological specimen which may be useful in development of methods for monitoring human drug exposure.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Intramural Research (Z01)
Project #
1Z01DA000235-01
Application #
3775040
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1993
Total Cost
Indirect Cost
Name
National Institute on Drug Abuse
Department
Type
DUNS #
City
State
Country
United States
Zip Code