Drug abuse has serious, often lethal, biomedical consequences, such as HIV infection and cardiovascular dysfunction. This project studies subject characteristics, high-risk behaviors, and other factors associated with such consequences, with the goal of developing interventions to prevent or ameliorate them. One study currently underway provides a comprehensive, non-invasive assessment of cardiovascular function in cocaine abusers, using 24-hour ambulatory monitoring of EKG, blood pressure, and heart rate; high-resolution EKG; analysis of heart rate variability (vagal tone), and echocardiography. Evaluation of the subclinical effects of acute and chronic cocaine use on cardiovascular function will help elucidate the mechanisms of cocaine's cardiovascular effects, hopefully leading to their prevention or amelioration.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Intramural Research (Z01)
Project #
1Z01DA000242-02
Application #
3752874
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1994
Total Cost
Indirect Cost
Name
National Institute on Drug Abuse
Department
Type
DUNS #
City
State
Country
United States
Zip Code