Basic mechanisms of the secretory process are studied in cells of the rat pancrease, salivary and lacrimal glands. Techniquies utilized include light and electron microscopy, enzyme- and immunocytochemistry, radioautography, and biochemistry. Major areas of investigation are: (1) the structure and function of the Golgi apparatus and GERL; (2) experimental pathology and lysosome function in salivary glands; (3) structure and permeability properties of junctional complexes in the rat parotid gland; (4) the role of salivary duct cells in protein reabsorption; (5) structure and cytochemistry of the salivary gland of the rat soft palate; and (6) parotid Beta-adrenergic receptor localization using labeled antagonists.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Intramural Research (Z01)
Project #
1Z01DE000028-18
Application #
4692587
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
18
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Dental & Craniofacial Research
Department
Type
DUNS #
City
State
Country
United States
Zip Code