Toxicokinetics of chlorpyrifos are being studied in F344 rats and B6C3F1 mice. Bioanalytical method for quantitation of chlorpyrifos and its main metabolite are being developed. Plasma concentrations of chlorpyrifos and its main metabolite will be determined after bolus iv injection of chlorpyrifos and gavage administration of chlorpyrifos. Bioavailability of chlorpyrifos will be estimated.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Intramural Research (Z01)
Project #
1Z01ES021177-01
Application #
3841050
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1992
Total Cost
Indirect Cost
City
State
Country
United States
Zip Code