Peroxisome Proliferators

Marsman, D.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Environmental Health Sciences (NIEHS)
• Type: Intramural Research (Z01)
• Project #: 1Z01ES021194-01
• Application #: 3755395
• Support Year: 1
• Fiscal Year: 1994

Institution

• Name: National Institute of Environmental Health Sciences
• Country: United States

Publications

Singh, V K; Ganesh, L; Cunningham, M L et al. (2001) Comparison of the mutant frequencies and mutation spectra of three non-genotoxic carcinogens, oxazepam, phenobarbital, and Wyeth 14,643, at the lambdacII locus in Big Blue transgenic mice. Biochem Pharmacol 62:685-92

O'Brien, M L; Twaroski, T P; Cunningham, M L et al. (2001) Effects of peroxisome proliferators on antioxidant enzymes and antioxidant vitamins in rats and hamsters. Toxicol Sci 60:271-8

O'Brien, M L; Cunningham, M L; Spear, B T et al. (2001) Effects of peroxisome proliferators on glutathione and glutathione-related enzymes in rats and hamsters. Toxicol Appl Pharmacol 171:27-37

Tharappel, J C; Cunningham, M L; Spear, B T et al. (2001) Differential activation of hepatic NF-kappaB in rats and hamsters by the peroxisome proliferators Wy-14,643, gemfibrozil, and dibutyl phthalate. Toxicol Sci 62:20-7

Rusyn, I; Denissenko, M F; Wong, V A et al. (2000) Expression of base excision repair enzymes in rat and mouse liver is induced by peroxisome proliferators and is dependent upon carcinogenic potency. Carcinogenesis 21:2141-5