The Norwegian Mother and Child study is a cohort study of pregnant women and their children in Norway. NIEHS is contributing to this effort by creating of a biological specimen repository to evaluate environmental exposures and health effects to pregnant women and their unborn children. As of July 31, 2006, 51,472 women had contributed biological samples (blood and urine) for the NIEHS portion of the study; 16,000 women were enrolled this fiscal year. These samples have been collected at 41 hospitals across Norway including urban centers and the Arctic regions. The enrollment target is 100,000 women. At the current recruitment rate we anticipate 80,000 women with blood and urine samples collected at 17 weeks gestation to evaluate for environmental exposures by the end of 2007.? ? During the past fiscal year, we published a manuscript on issues related to urine storage and environmental exposures (phenols, phthalates, non-persistent pesticides) and have a manuscript in press regarding the biological specimen bank. In collaboration with Norwegian investigators, we are implementing a quality assurance experiment and protocol to assess storage conditions for a variety of parameter. Results of the initial quality assurance measures were presented at a professional meeting in October 2004 and a manuscript is currently in preparation.
| Whitworth, Kristina W; Haug, Line S; Baird, Donna D et al. (2012) Perfluorinated compounds and subfecundity in pregnant women. Epidemiology 23:257-63 |
| Håberg, Siri E; London, Stephanie J; Nafstad, Per et al. (2011) Maternal folate levels in pregnancy and asthma in children at age 3 years. J Allergy Clin Immunol 127:262-4, 264.e1 |
| Furu, Kari; Karlstad, Oystein; Skurtveit, Svetlana et al. (2011) High validity of mother-reported use of antiasthmatics among children: a comparison with a population-based prescription database. J Clin Epidemiol 64:878-84 |
| Hancock, Dana B; Håberg, Siri E; Furu, Kari et al. (2011) Oral contraceptive pill use before pregnancy and respiratory outcomes in early childhood. Pediatr Allergy Immunol 22:528-36 |
| Eggesbo, Merete; Stigum, Hein; Longnecker, Matthew P et al. (2009) Levels of hexachlorobenzene (HCB) in breast milk in relation to birth weight in a Norwegian cohort. Environ Res 109:559-66 |
| Paltiel, Liv; Ronningen, Kjersti S; Meltzer, Helle M et al. (2008) Evaluation of Freeze Thaw Cycles on stored plasma in the Biobank of the Norwegian Mother and Child Cohort Study. Cell Preserv Technol 6:223-230 |
| Nguyen, Ruby H N; Wilcox, Allen J; Skjaerven, Rolv et al. (2007) Men's body mass index and infertility. Hum Reprod 22:2488-93 |
| Ronningen, Kjersti S; Paltiel, Liv; Meltzer, Helle M et al. (2006) The biobank of the Norwegian Mother and Child Cohort Study: a resource for the next 100 years. Eur J Epidemiol 21:619-25 |
| Hoppin, Jane A; Ulmer, Ross; Calafat, Antonia M et al. (2006) Impact of urine preservation methods and duration of storage on measured levels of environmental contaminants. J Expo Sci Environ Epidemiol 16:39-48 |
