Aims: 1) To examine the relation between maternal serum levels of the androgenic DDT metabolite DDE in relation to anogenital distance in 200 male newborns in Tapachula, Mexico, where there has been recent, high-level exposure to DDT, 2) To conduct a pilot study of the relation of maternal DDE levels to risk of preterm birth (n=75 cases, 150 controls). Accomplishments: The study should go into the field in July of 2001. Pilot data have confirmed the high exposure levels and the feasibility of measuring anogenital distance in Mexico.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Intramural Research (Z01)
Project #
1Z01ES044009-01
Application #
6535037
Study Section
Epidemiology and Biometry Training Committee (EB)
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
2001
Total Cost
Indirect Cost
Name
U.S. National Inst of Environ Hlth Scis
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Cupul-Uicab, Lea A; Terrazas-Medina, Efraín A; Hernández-Ávila, Mauricio et al. (2014) Prenatal exposure to p,p'-DDE and p,p'-DDT in relation to lower respiratory tract infections in boys from a highly exposed area of Mexico. Environ Res 132:19-23
Cupul-Uicab, Lea A; Gladen, Beth C; Hernandez-Avila, Mauricio et al. (2009) Reliability of reported breastfeeding duration among reproductive-aged women from Mexico. Matern Child Nutr 5:125-37
Romano-Riquer, S Patricia; Hernandez-Avila, Mauricio; Gladen, Beth C et al. (2007) Reliability and determinants of anogenital distance and penis dimensions in male newborns from Chiapas, Mexico. Paediatr Perinat Epidemiol 21:219-28
Longnecker, Matthew P (2005) Invited Commentary: Why DDT matters now. Am J Epidemiol 162:726-8
Salazar-Martinez, Eduardo; Romano-Riquer, Patricia; Yanez-Marquez, Edith et al. (2004) Anogenital distance in human male and female newborns: a descriptive, cross-sectional study. Environ Health 3:8