The primary objective of this study is to evaluate the degree of variability in retinal measurements of lutein, a carotenoid macular pigment of human retina, with a new and novel technique of resonant Raman scattering spectroscopy. This technique is generally more objective than psychophysical techniques used for lutein measurements, such as heterochromatic flicker photometry. The technique is non-invasive, and the levels of ocular exposure to argon laser light with the Raman device are well below the safety limits specified by American National Standards Institute regulations. Twenty normal volunteers with normal visual function will be enrolled and the reproducibility of the resonant Raman scattering spectroscopy will be evaluated.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Intramural Research (Z01)
Project #
1Z01EY000412-01
Application #
6826978
Study Section
(ECSB)
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
2003
Total Cost
Indirect Cost
Name
U.S. National Eye Institute
Department
Type
DUNS #
City
State
Country
United States
Zip Code