This project will develop statistical methodology to examine the data collected by NICHD through the projects Small-for-Gestational Age Study I and Study II in Alabama and Scandinavia, and the projects Maternally Linked Longitudinal Studies in Missouri and Utah. A host of statistical procedures will be developed to handle questions concerning various issues in perinatal epidemiology. Methodologically, it is planned to generate new and rigorous statistical methods and algorithms that can generally be applied to studies involving repeatedly measured data. The first phase of the project focuses on the fetal growth applications, maternal risk factors, and pregnancy outcomes.
| Vexler, Albert; Wu, Chengqing; Yu, Kai Fun (2010) Optimal Hypothesis Testing: From Semi to Fully Bayes Factors. Metrika 71:125-138 |
| Wu, Mi-Xia; Yu, Kai-Fun; Liu, Ai-Yi (2009) Estimation of Variance Components in the Mixed-Effects Models: A Comparison Between Analysis of Variance and Spectral Decomposition. J Stat Plan Inference 139:3962-3973 |
| Zhang, Jun; Villar, Jose; Sun, Wenyu et al. (2007) Blood pressure dynamics during pregnancy and spontaneous preterm birth. Am J Obstet Gynecol 197:162.e1-6 |
| Levine, Richard J; Lam, Chun; Qian, Cong et al. (2006) Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. N Engl J Med 355:992-1005 |
| Levine, Richard J; Qian, Cong; Maynard, Sharon E et al. (2006) Serum sFlt1 concentration during preeclampsia and mid trimester blood pressure in healthy nulliparous women. Am J Obstet Gynecol 194:1034-41 |
| Signore, Caroline; Mills, James L; Qian, Cong et al. (2006) Circulating angiogenic factors and placental abruption. Obstet Gynecol 108:338-44 |
| Troendle, James F; Liu, Aiyi; Wu, Chengqing et al. (2005) Sequential testing for efficacy in clinical trials with non-transient effects. Stat Med 24:3239-50 |
| Liu, Aiyi; Wu, Chengqing; Yu, Kai F et al. (2005) Supplementary analysis of probabilities at the termination of a group sequential phase II trial. Stat Med 24:1009-27 |
| Levine, Richard J; Qian, Cong; Leshane, Erik S et al. (2004) Two-stage elevation of cell-free fetal DNA in maternal sera before onset of preeclampsia. Am J Obstet Gynecol 190:707-13 |
| Klebanoff, Mark A; Schwebke, Jane R; Zhang, Jun et al. (2004) Vulvovaginal symptoms in women with bacterial vaginosis. Obstet Gynecol 104:267-72 |
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