A collaborative linkage study of breast cancer families that are not segregating mutations at either the BRCA1 or BRCA2 loci has been inititated this fiscal year. Power studies have been performed to pick the most informativefamilies for the search for a third BRCA gene and genotyping is about to start on these samples.
| Marroni, F; Aretini, P; D'Andrea, E et al. (2004) Evaluation of widely used models for predicting BRCA1 and BRCA2 mutations. J Med Genet 41:278-85 |
| Huusko, Pia; Juo, Suh-Hang Hank; Gillanders, Elizabeth et al. (2004) Genome-wide scanning for linkage in Finnish breast cancer families. Eur J Hum Genet 12:98-104 |
| Rozenblum, Ester; Vahteristo, Pia; Sandberg, Therese et al. (2002) A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes. Hum Genet 110:111-21 |
| Baffoe-Bonnie, A B; Beaty, T H; Bailey-Wilson, J E et al. (2000) Genetic epidemiology of breast cancer: segregation analysis of 389 Icelandic pedigrees. Genet Epidemiol 18:81-94 |
| Kainu, T; Juo, S H; Desper, R et al. (2000) Somatic deletions in hereditary breast cancers implicate 13q21 as a putative novel breast cancer susceptibility locus. Proc Natl Acad Sci U S A 97:9603-8 |
