Nuclear Magnetic Resonance and Mass Spectroscopy are complementary instrumental methods for structural determination of organic and bio- organic chemical compounds. The determination of the structure of several indole alkaloids from the seeds of Picralima nitida has been completed. A new indole alkaloid, picratidine, was found. Control studies for a project to examine antibody binding by deuterium NMR are in progress.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Intramural Research (Z01)
Project #
1Z01HL001002-16
Application #
3878920
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
16
Fiscal Year
1990
Total Cost
Indirect Cost
Name
National Heart, Lung, and Blood Institute
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Mace, Lisa C; Yermalitskaya, Liudmila V; Yi, Yajun et al. (2009) Transcriptional remodeling of rapidly stimulated HL-1 atrial myocytes exhibits concordance with human atrial fibrillation. J Mol Cell Cardiol 47:485-92