New modes of Doppler ultrasound and new signal conditioning of the received sonic specta permit accurate assessment of mean and peak velocities of intracardiac blood flow. Color encoded, two dimensional Doppler permits qualitative and quantitative evaluations of entire flow field velocity patterns. Studies utilizing these technologies include the following: (1) Quantitation of gradients in Newfoundland dogs with subaortic stenosis; (2) Comparison of ultrasound Doppler with laser Doppler anemometry; (3) Studies of intracardiac shunt flow; (4) Doppler color flow mapping of prosthetic mitral valves; and (5) Quantitation of obstruction and regurgitation in right ventricular to pulmonary arter conduits with and without prosthetic values. Studies in patients, both intraoperatively and postoperatively, have been initiated for the assessment of operations for valvular lesions and congenital cardiac defects.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Intramural Research (Z01)
Project #
1Z01HL002742-02
Application #
4694598
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1985
Total Cost
Indirect Cost
Name
U.S. National Heart Lung and Blood Inst
Department
Type
DUNS #
City
State
Country
United States
Zip Code